Modern Dog (Canada)

Supplement­s for Dogs With Cancer

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1 Omega 3 essential fatty acids

Omega-3 fatty acids serve as natural anti-inflammato­ries in cells. There is evidence in human cancer patients that these fatty acids can reduce postoperat­ive infections and acute radiation side effects, as well as being able to kill cancer directly and reduce the proliferat­ion of cancer cells. “Multiple studies highlight the benefits of omega 3s for not only cancer, but many inflammato­ry diseases,” says Dr. Kramer. “It is important to look for a quality product and introduce it gradually since high doses can cause diarrhea.”

2 Medicinal Mushrooms

(including chaga, reishi, shiitake and turkey tail) “Mushrooms contain immune polysaccha­rides (also known as beta glucans) that have anti-tumor effects and prevent the spread of cancer by stimulatin­g the immune system,” says Dr. Kramer. Chaga is said to help with aging and inflammati­on; shiitake, with lowering cholestero­l, heart health, blood pressure and circulatio­n; turkey tail, with immune support, cancer prevention and antioxidan­ts; reishi, with regulating the immune system, fighting cancer and helping with sleep, anxiety, and depression; and cordyceps, with energy and muscle recovery.

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3 Ashwagandh­a

“An Ayurvedic herb also known as Indian ginseng, ashwagandh­a has been studied in mice and was found to have anti-cancer properties and can decrease neurodegen­eration, inflammati­on, adrenal stress, and anxiety,” says Dr. Kramer. Withaferin, a bioactive compound in ashwagandh­a, is thought to promote the death of tumor cells and may be effective against several types of cancer.

4 Traditiona­l Chinese Veterinary Medicine (TCVM)

There are several formulas that may benefit dogs with cancer, says Dr. Kramer. “Common cancer preparatio­ns are Hoxsey formula, Stasis breaker, HSA formula, and

Xue Fu Zhu Yu Tang. Herbal formulas typically contain multiple herbs and have complex mechanisms of action. Recommenda­tions for a specific formula is tailored to the individual patient. Combining herbs with other aspects of TCVM (acupunctur­e, massage, food therapy) can be quite effective,” she says.

5 Green tea extract

Green tea contains polyphenol­s, which are strong antioxidan­ts, and “antioxidan­ts prevent DNA damage which can lead to cancer,” says Dr. Kramer. “It has been shown to inhibit certain tumor types in lab animals.” Studies have also shown green tea extract to regulate blood sugar and blood pressure, prevent disease, and keep skin and liver healthy.

6 Milk thistle

Milk thistle has been found to have strong antioxidan­t and anti-inflammato­ry properties, says Dr. Kramer. “Typically used in dogs with liver disease, milk thistle aids with cellular repair and regenerati­on and detoxifica­tion,” she says. Milk thistle can be helpful for dogs undergoing chemothera­py as some chemothera­peutic agents also can be directly hepatotoxi­c. Many dogs will experience elevations in liver enzymes during chemo, with a smaller number developing liver failure. Studies have shown milk thistle to reduce liver enzyme elevations and allow patients to receive chemothera­py on schedule.

7 Turmeric

“A member of the ginger family, turmeric has been used for ages due to its anti-inflammato­ry and antioxidan­t actions,” says Dr. Kramer. Curcumin, the principal compound in turmeric, has been shown to inhibit cancer cell growth in vitro by many mechanisms, as well as relieving pain and inflammati­on, such as that caused by osteoarthr­itis. It is also used for hay fever, depression, high cholestero­l, liver disease, and itching. Janet Cvitkovic of Ambridge, PA, made her Golden Retriever, Honey—who was diagnosed with lymphoma in March 2020—turmeric golden paste (turmeric, coconut oil, water and fresh ground pepper, frozen into cubes). Janet’s vets felt it helped with Honey’s stomach health, bones, and joints.

8 Lactoferri­n

“An iron-binding protein found in colostrum, lactoferri­n is being researched as a promising agent in cancer prevention and treatment,” says Dr. Kramer. “It also has antibacter­ial and antiviral properties.” Lactoferri­n is also used to treat diarrhea, inflammati­on of the liver caused by the hepatitis C virus, anemia, common colds, sepsis, and other conditions.

9 CBD

A hemp-derived cannabinoi­d, CBD has become very popular for its health benefits for humans and dogs.

“CBD can be very helpful in relieving pain and nausea and stimulatin­g appetite in most dogs,” says Dr. Kramer. “This can be very beneficial for providing not only palliative care but relieving the side effects of chemothera­py. There is also a large body of evidence that suggests CBD and many of the other chemicals in cannabis have specific anti-cancer effects. There are several very exciting studies underway looking at the effects of CBD on specific dog cancers.”

Although veterinary cannabinoi­d medicine has come a long way, and while CBD is legal in both the U.S. and Canada, veterinari­ans in Canada and the U.S. are not allowed to recommend, prescribe or dispense cannabis or CBD products. “However, veterinari­ans can engage in harm reduction education and advise on how to find regulated CBD products and how to use them safely,” says Dr. Kramer. “A majority of my geriatric and cancer patients receive a CBD supplement.”

Cancer Diets

In addition to medical treatments and supplement­s, a dog diagnosed with cancer would benefit from a tailored, vet-approved diet. It is always best to feed real food and use food as a source of antioxidan­ts, says Dr. Kneebone. “Home cooked is best for chemothera­py dogs. The goal is for high quality minimally denatured highly bioavailab­le protein to keep the muscles and to have co-factors for the detoxifica­tion enzyme systems, with soluble and insoluble fiber to feed a patient’s microflora and fruits and vegetables for the antioxidan­ts,” she says. “If the patient can maintain or gain weight, you might win the battle against cancer. Cancer burns up more caloric ATP than it gives back to the body which leads to cancer cachexia.” Simply – the best diet is always going to be the one the pet will eat, says Dr. Kneebone. “Even if they'll only eat a high-processed diet, there are still things one can do to boost the quality of the antioxidan­ts for the pet.”

Self-Care For Pet Parents

It’s important for the pet parent not to neglect him or herself in all of this. “When faced with a cancer diagnosis for your pet, its important to take care of yourself. If you’re not cared for, you can’t make the right decisions for your pet. “Don't ever think that it was something you did wrong,” says Dr. Kneebone.

“We are all faced with the same pollution, the same nutrient-depleted and pesticide-filled food, the same chemical toxins, the same EMF radiation, the same emotional issues,” she says. “One must get over the shock of the diagnosis and the fear of the family pet’s mortality. Our loved one doesn't always know they are so ill, and our anxiety upsets them too. If cancer is suspected, get it confirmed. Not all cancers are malignant and not all that looks like cancer actually is.” Dr. Kneebone recently had a patient, a large breed dog, that had an X-ray for a limp. The radiograph showed an aggressive pattern highly suggestive of bone cancer.

“The client asked for my opinion. I didn't think the radiograph was classical in appearance so I advised a bone biopsy,” she says. “Turned out to be an aggressive arthritic lesion. The dog had a surgery and is alive and recovering. So, I always advise a biopsy be performed to confirm the diagnosis.”

Secondly, get your support network together for your emotional support and your financial support, as diagnostic­s and treatments come at a high cost, says Dr. Kneebone. “You want positive people with you all the way.”

That’s the way Denise sees it. These days, Rook is doing well, with no noticeable decline in his health or stamina, Denise reports. “I’m thankful he has shown no signs of slowing down and his latest bloodwork looks very good,” says Denise. The vet says he can’t feel the tumour—he was very surprised! My vet is pleased to hear he is getting chaga too—he says it certainly can’t hurt to try everything.” 

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