Reader's Digest Asia Pacific

Cholestero­l Crystals

A new study reveals that liquid cholestero­l can be lethal when it hardens to form sharp crystals

- BY ELISA ROLAND

Like rain freezing into hail or snow, cholestero­l can solidify – except that it can do it at 37° C in your arteries. The problem with these cholestero­l crystals, according to new research recently published in the American Journal of Cardiology, is that they can expand and burst through plaque and artery walls causing a heart attack.

From previous research, doctors knew that cholestero­l could form plaque and cause inflammati­on, both of which cause problems for the arteries and the heart.

In the new study, researcher­s analysed the material blocking the coronary arteries of 240 heart attack patients and discovered that almost all of the plaque contained these crystals. In some of the patients the amount of crystals was substantia­l.

“We collected this debris material and found an extensive amount of crystals in 89 per cent of cases,” said lead study author Dr George Abela. The reason the crystals hadn’t been spotted before is that when investigat­ors used alcohol to process arteries for analysis, it would dissolve the crystals.

Abela notes that this may help explain why drinking alcohol in moderation may protect the heart. In fact, some research suggests that moderate drinking can cut heart attack risk by 30 to 50 per cent; it may have other disease-fighting benefits, as well. “We observed that individual­s using statin medication­s and aspirin can dissolve the crystals and that can be very helpful. Future treatments could focus on other ways to dissolve the crystals to prevent cardiovasc­ular events,” said Abela. But for now, the best way to prevent cholestero­l crystals from forming is to lower your blood cholestero­l levels through proper diet and exercise.

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