Knockout gas could drive risk of cancer
After looking around at venues, Michael said ‘what about a theme park?’ and by the end of the week they were booked in at Movie World.
“We’re not really conventional I guess,” Ms Murakami joked.
The Sunday Mail also gathered wedding pictures of Matthew and Sarah Burgess, the first couple to tie the knot on South Bank’s Brisbane Wheel.
Other couples celebrated their night with inspirations from their favourite book/ movie, with a Harry Potterthemed wedding where the groomsmen carried wands, to dazzling on the dancefloor in a Great Gatsby wedding. One couple recreated the blue door image in their Doctor Whothemed wedding. FEARS that drugs used during cancer surgery may be causing diseases to return have prompted a major study into anaesthetic gas.
With Australian cancer patients undergoing more than 300,000 operations with the use of anaesthetic each year, Melbourne researchers will lead an international study that is likely to change surgical strategies worldwide.
The Federal Government has backed the Peter MacCallum Cancer Centre research after a review of cancer cases found a significantly higher rate of the disease recurring among patients anaesthetised by inhaling gas than those under intravenous anaesthetic.
The alarm is being further sounded by a Melbourne study that found mice treated with gas anaesthetic had a much greater chance of their cancer returning than those sedated via an intravenous drip.
With 80 per cent of Australian and New Zealand anaesthetists preferring the decadesold “volatile” gases rather than the newer intravenous drug propofol, chief investigator Professor Bernhard Riedel said it was vital the long-term impact was better understood.
“We suspect that these volatiles may drive cancer recurrence,” Prof Riedel said.
“The properties of these volatiles are pro-inflammatory, pro-anogenic, immunesuppressant, and it may add fuel to the fire rather than help with the stress of the surgery.”
Surgery remains the most common treatment for cancer, with eight out of 10 patients exposed to an anaesthetic, including 60 per cent who have it as their primary treatment.
While the surgery is essential to remove many cancers the trauma produces an inflammatory response.
Prof Riedel said the use of traditional gas anaesthesia may be introducing a drug that suppresses the immune system, allowing any microscopic left over sections of tumour to grow.
Under a $4.8 million National Health and Medical Research Council grant, Prof Riedel will lead researchers from Australia, the US, UK, Ireland and other nations to set up a five-year study of 5700 patients undergoing cancer surgery, to determine if the intravenous drug propofol is safer.
Supported by the Royal Australian and New Zealand College of Anaesthetists, the study will also examine the use of intravenous treatment lidocaine to determine if the two drugs can reduce cancer progression after surgery.
Although retrospective studies also show a spike in cancer recurrence 18 months and 36 months after surgery among patients anaesthetised with gas, Prof Riedel said the findings were not yet strong enough to change guidelines.
“My clinical practise has altered, but the greater community’s practise has not,” he said. “If the signal is definitely there and it is strong we will make sure it is disseminated globally.”