If you have a bone to pick with someone, you are angry with that person about something, and you want to discuss it.
Loads (ifml.) means a large number or amount of something.
“Do” is usually the correct word to use when talking about work: “do the housework” or do the baking. “Make” is used to express the idea of creating something, as in “make a cake”.
When you sit down and relax, especially with your feet raised and supported, you put your feet up.
If you are able to deal successfully with a large amount of work or a tricky task, you can say you can handle it.