In­no­va­tion: Pills that de­liver in­jec­tion-only drugs

Bloomberg Businessweek (Europe) - - NEWS -

Form and func­tion

Ge­net­i­cally en­gi­neered drugs known as bi­o­log­ics typ­i­cally have to be in­jected rather than swal­lowed be­cause their com­plex pro­teins break down in the stom­ach. Rani Ther­a­peu­tics is de­vel­op­ing a pill that will pro­tect those pro­teins.

Next Steps

Rani’s pills will need to win U.S. reg­u­la­tory ap­proval as both a drug and a med­i­cal de­vice, de­liv­er­ing the proper dose of medicine and mak­ing sure the tiny bal­loon passes harm­lessly out of the pa­tient’s body. John Yin, pro­fes­sor of chem­i­cal and bi­o­log­i­cal engi­neer­ing at the Univer­sity of Wis­con­sin at Madi­son, says the suc­cess of the com­plex process may also de­pend some­what on the nat­u­ral dif­fer­ences in pa­tients’ in­testi­nal tracts. Im­ran says he hopes to start hu­man tri­als next year. ——Michelle Fay Cortez

In­no­va­tor Mir Im­ran Age 59Ti­tle Founder of Rani Ther­a­peu­tics, based in San Jose

Newspapers in English

Newspapers from Bahrain

© PressReader. All rights reserved.