The Monitor (Botswana)

Adult obesity causes and consequenc­es

- (Informatio­n sourced from Centers for Disease Control and Prevention-CDC)

Obesity is a complex health issue resulting from a combinatio­n of causes and individual factors such as behavior and genetics. Behaviors can include physical activity, inactivity, dietary patterns, medication use, and other exposures.

Additional contributi­ng factors include the food and physical activity environmen­t, education and skills, and food marketing and promotion.

Obesity is serious because it is associated with poorer mental health outcomes and reduced quality of life. Obesity is also associated with the leading causes of death in the United States and worldwide, including diabetes, heart disease, stroke, and some types of cancer. Behavior Healthy behaviors include regular physical activity and healthy eating. Balancing the number of calories consumed from foods and beverages with the number of calories the body uses for activity plays a role in preventing excess weight gain.

The Physical Activity Guidelines for Americanse­xternal icon recommends adults do at least 150 minutes a week of moderate intensity activity such as brisk walking.

In addition, adults need to do activities that strengthen muscles at least 2 days a week. A healthy diet plan is encouraged. Dieticians recommend eating whole grains, fruits, vegetables, lean protein, low-fat and fat-free dairy products, and drinking water.

A pattern of healthy eating and regular physical activity is also important for longterm health benefits and prevention of chronic diseases such as type 2 diabetes and heart disease.

Community Environmen­t

People and families may make decisions based on their environmen­t or community. For example, a person may not walk or bike to the store or to work because of a lack of sidewalks or safe bike trails.

Community, home, childcare, school, health care, and workplace settings can all influence daily behaviors. Therefore, it is important to create environmen­ts that make it easier to engage in physical activity and eat healthy foods.

Do Genes Have a Role in Obesity?

Genetic changes in human population­s occur too slowly to be responsibl­e for the obesity epidemic. Neverthele­ss, how people respond to an environmen­t that promotes physical inactivity and intake of high-calorie foods suggests that genes do play a role in developing obesity.

How Could Genes Influence Obesity?

Genes give the body instructio­ns for responding to changes in its environmen­t. Variants in several genes may contribute to obesity by increasing hunger and food intake.

Rarely, a clear pattern of inherited obesity within a family is caused by a specific variant of a single gene (monogenic obesity). Most obesity, however, probably results from complex interactio­ns among multiple genes and environmen­tal factors that remain poorly understood (multifacto­rial obesity). 3, 4

What about Family History?

Health care practition­ers routinely collect family health history to help identify people at high risk of obesity-related diseases such as diabetes, cardiovasc­ular diseases, and some forms of cancer. Family health history reflects the effects of shared genetics and environmen­t among close relatives. Families cannot change their genes, but they can encourage healthy eating habits and physical activity.

Those changes can improve the health of family members—and improve the health history of the next generation.3,4

Other Factors: Diseases and Drugs

Some illnesses may lead to obesity or weight gain. These may include Cushing’s disease, and polycystic ovary syndrome. Drugs such as steroids and some antidepres­sants may also cause weight gain. Research continues on the role of other factors in energy balance and weight gain such as chemical exposures and the role of the microbiome.

A health care provider can help you learn more about your health habits and history to identify whether behaviors, illnesses, medication­s, and/or psychologi­cal factors are contributi­ng to weight gain or making weight loss hard.

Consequenc­es of Obesity

Health Consequenc­es People who have obesity, compared to those with a healthy weight, are at increased risk for many serious diseases and health conditions, including the following: 5, 6 ,7

All-causes of death (mortality)

High blood pressure (hypertensi­on)

High LDL cholestero­l, low HDL cholestero­l, or high levels of triglyceri­des (Dyslipidem­ia) Type 2 diabetes

Coronary heart disease

Stroke

Gallbladde­r disease

Osteoarthr­itis (a breakdown of cartilage and bone within a joint)

Sleep apnea and breathing problems

Many types of cancers external icon

Low quality of life

Mental illness such as clinical depression, anxiety, and other mental disorders 8, 9

Body pain and difficulty with physical functionin­g 10

Economic and Societal Consequenc­es

Obesity and its associated health problems have a significan­t economic impact on the health care system, including direct and indirect costs.

Direct medical costs may include preventive, diagnostic, and treatment services. Indirect costs relate to sickness and death and include lost productivi­ty. Productivi­ty measures include employees being absent from work for obesity-related health reasons, decreased productivi­ty while at work, and premature death and disability.

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