Calgary Herald

Gorilla genome sheds light on human evolution

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Scientists have sequenced the genome of the gorilla, the last great ape to have its genes decoded, and say it gives new insights into difference­s between the apes and humans — including their ability to produce competitiv­e sperm.

While confirming that our closest relative is the chimpanzee, the research also shows that around 15 per cent of the human gene map resembles the gorilla more closely than it does the chimpanzee genome.

Chris Tyler-smith, who worked with a team of scientists who presented their findings in a telephone briefing, said that while many human genes are similar to the gorilla versions, it is the ones that differ that are often most intriguing. One difference that stuck out was in the genes involved in sperm production, he said.

“Gorillas live in groups with one male and lots of females, so there’s not much opportunit­y for sperm competitio­n,” he said. “It was interestin­g for us to see that some genes involved in sperm formation . . . had either become inactive in gorillas or had decreased in copy number.”

The study was published in the journal Nature on Wednesday.

The team used DNA from a western lowland gorilla to assemble a gorilla genome sequence and then compared it with the gene maps of the other great apes.

“The gorilla genome is important because it tells us about that crucial time when we were diverging from our closest evolutiona­ry cousins,” said Aylwyn Scally of Britain’s Wellcome Trust Sanger Institute, who led the research team.

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