Calgary Herald

E-cigarette company Juul is working on device to curb nicotine addiction

Technology can allow consumers to limit intake, U.S. patent applicatio­n shows

- CATHERINE MCINTYRE

As it tries to get ahead of a regulatory crackdown on the vaping industry, e-cigarette company Juul Labs has applied for a patent on a new device it claims will use machine learning to help wean people off nicotine.

A patent applicatio­n filed in the U.S. in June 2019 and made public last month details the company’s intellectu­al property claim for technology that it says can be programmed to gradually reduce the amount of nicotine its devices deliver to users.

“E-cigarettes have been shown to help smokers displace their addiction from combusted cigarettes to e-cigarettes and may offer a harm reduced alternativ­e,” the applicatio­n reads. “In some aspects, nicotine-free e-cigarettes may contain sensory stimulants, such as citric acid.”

The applicatio­n describes a device that delivers multiple vaping substances: one that includes nicotine, for example, and at least one other that has no nicotine or a very low dose of the drug.

Users can tailor its settings to their own program for quitting nicotine, the applicatio­n says. For example, they can set the e-cigarette to deliver a hit of nicotine only in the first puff or two, and have it kick out a “sensory stimulant” like citric acid in subsequent hits. They can also cap their daily nicotine intake and have the device notify them or lock them out once they’ve reached it.

The device, which could be synced with a mobile app, would also include a machine learning component that could adjust features like nicotine concentrat­ion and delivery patterns based on “inputs” the user provides, either by actively giving feedback or having the device learn by monitoring vaping behaviour. “For example, at later stages of the cessation program the machine learning algorithm may increase the ratio of citric acid puffs and may determine that first few puffs of vaporizer session are nicotine and then after that citric acid puffs may give the user a similar level of satisfacti­on,” the applicatio­n reads.

“The fact that we have filed for such patent protection does not mean JUUL Labs will move forward with the commercial developmen­t of any particular technologi­cal concept,” a Juul spokespers­on told The Logic in an email. “We remain focused on resetting the vapour category and earning the trust of society by working co-operativel­y with attorneys general, regulators, public health officials, and other stakeholde­rs to combat underage use and transition adult smokers from combustibl­e cigarettes.

The medical community is divided on whether e-cigarettes can help people quit smoking. Public Health England maintains that vaping is 95-per-cent less harmful than smoking cigarettes, and the U.K.’S Royal College of Physicians directs doctors to promote e-cigarettes “as widely as possible” to patients trying to quit smoking.

Health officials in Canada, meanwhile, have called for regulators to impose the same restrictio­ns as they have for the tobacco industry, and for more research into the health implicatio­ns of e-cigarettes before recommendi­ng them as harm-reduction tools.

The discussion has grown more urgent amid an onslaught of vaping-related lung injuries and an uptick in nicotine-use among young people. As of Feb. 4, 2,758 e-cigarette users in the U.S. have been hospitaliz­ed, 64 of whom have died; the majority of cases involved patients under 25 years old and vaping products that included vitamin E acetate and THC — the psychoacti­ve chemical in cannabis — which Juul doesn’t sell. There have been 18 reported cases in Canada, as of Feb. 18.

North American regulators have begun responding with restrictio­ns on the marketing and sale of e-cigarette products. In December 2019, Nova Scotia became the first province to ban sales of flavoured vaping products, effective April 1; B.C. and Ontario are considerin­g similar rules. Health Canada, meanwhile, is reviewing the federal laws governing vaping, enacted less than two years ago, with potential updates including a ban on ads in public spaces and countrywid­e restrictio­ns on flavours.

In the U.S., President Donald Trump announced rules banning certain vape flavours in January, and the Food and Drug Administra­tion (FDA) is giving e-cigarette makers until May to prove their products deliver a net benefit to the public in order to keep selling them.

Juul has tried to get in front of the regulatory pushback, removing all flavoured products from the U.S. market over the last two years and, as The Logic first reported last month, temporaril­y halting their production in Canada.

But it has nonetheles­s been a blow to Juul’s business, once worth an estimated US$38 billion. Tobacco giant Altria has written down its Us$12.8-billion investment in the firm by US$8.6 billion, now valuing the company at about US$12 billion, and The Wall Street Journal reported on Friday that the U.S. Securities and Exchange Commission was investigat­ing whether Altria had properly disclosed to its shareholde­rs the risks associated with the investment. Juul laid off 650 employees in the wake of the controvers­y and announced it would cut spending by US$1 billion, shifting its focus from marketing to regulatory compliance. “As the vapour category undergoes a necessary reset, this reorganiza­tion will help Juul Labs focus on reducing underage use, investing in scientific research, and creating new technologi­es while earning a license to operate in the U.S. and around the world,” CEO K.C. Crosthwait­e said in a statement following the cuts.

In a report published earlier this month, Roberto Pozzi, a London-based credit analyst at Moody’s Investors Service, predicted that regulation­s would continue hurting the sector over the next 12 to 18 months. Bouncing back, he said, will depend on convincing lawmakers that new products are safer than cigarettes. “If regulators recognize even some of the reduced risk claims of the new categories and consumptio­n stabilizes, this will help the sector’s credit quality in the longer term by preserving revenue,” he wrote.

Developing a technology that can taper nicotine intake could signal to regulators that the company is prepared to comply with their new rules, said Stanton Glantz, a medical professor and director of the Center for Tobacco Control Research and Education at the University of California, San Francisco. But Glantz warned this particular technology could cause even more harm than Juul’s earlier e-cigarettes.

“As a matter of policy, should not permit this,” he said in an interview with The Logic.

Glantz’s main concerns were about privacy — that Juul would have access to the personal health and location data of its customers through the device’s two-way communicat­ion abilities — and that an algorithm could control the nicotine concentrat­ions its vapes deliver, potentiall­y making the products more addictive. The company did not answer The Logic’s questions about how the technology it’s considerin­g would control nicotine concentrat­ions and other vaping features.

He also raised doubts about the device’s ability to wean users off nicotine, adding that creating a device that curbs nicotine dependence would be a death knell to Juul’s business. “They’re saying we’re gonna have this product so people can wean themselves off nicotine, but then they’re off the product. I don’t think Juul’s interested in putting themselves out of business.”

For more news about the innovation economy, visit www.thelogic.co

 ?? AJENG DINAR ULFIANA/REUTERS FILES ?? Juul says it remains focused on working to help “combat underage use and transition adult smokers from combustibl­e cigarettes.” Juul says it’s not certain it will move forward with commercial developmen­t of a new device that aims to help users quit nicotine.
AJENG DINAR ULFIANA/REUTERS FILES Juul says it remains focused on working to help “combat underage use and transition adult smokers from combustibl­e cigarettes.” Juul says it’s not certain it will move forward with commercial developmen­t of a new device that aims to help users quit nicotine.
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