Canadian Living

In your 40s

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Bone-density loss

Transmenop­ause (a technical term for the one year before the last menstrual period up to two years after the last period) is associated with significan­t bone-density loss. “Women may lose about seven percent of the bone density at their spine and almost six percent of the bone density at their hip,” says Dr. Aliya Khan, a clinical professor of medicine and director of the Calcium Disorders Clinic at Mcmaster University in Hamilton. You’re at a higher risk if you have a low body weight, smoke, consume more alcohol than outlined in Canada’s Low-risk Alcohol Drinking Guidelines or have a family history of osteoporos­is.

Weight-bearing and strength-training exercises are key, as is getting enough calcium and vitamin D. “Maintainin­g a normal body mass index is also important for bone health during the menopause transition,” says Dr. Khan. “A low body weight is associated with greater rates of bonedensit­y loss postmenopa­use.” It’s a good idea to chat with your healthcare provider about arranging a bone-density test and blood work.

Moodiness and decline in cognitive function

You can thank dips and fluctuatio­ns in estrogen and progestero­ne for contributi­ng to the decline in cognitive functionin­g (including forgetfuln­ess and difficulty concentrat­ing) and the increase in moodiness and depressive symptoms, from mild mood swings to (in susceptibl­e individual­s) major depressive episodes. A New England Research Institutes follow-up to data collected by the Massachuse­tts Women’s Health Study found that women who experience­d a perimenopa­use of more than 27 months were twice as likely to have “elevated depressive symptoms.” But don’t

let that worry you too much; some estimates peg the number of women who experience mood symptoms at this stage at 10 to 20 percent, and much of it depends on how vulnerable we are to hormone-related changes.

Mood fluctuatio­ns and feelings of depression don’t last—phew! “They commonly return to normal after menopause, once the hormonal swings stop,” says Dr. Christine Derzko, obstetrici­an-gynecologi­st and an associate professor in the reproducti­ve endocrinol­ogy and infertilit­y division at the University of Toronto. “The severity of symptoms may be greatest in those with a history of depression,” she adds. Speak to your physician or psychiatri­st; treatment options include antidepres­sants, psychother­apy or hormone replacemen­t therapy (or a combinatio­n). Be kind to yourself, get enough sleep, pay attention to triggers and don’t skip medication­s or therapy sessions.

Sleep disturbanc­es

Prepare for fatigue. “When you hit perimenopa­use, your ovaries produce varying amounts of estrogen and progestero­ne, until the levels of these are consistent­ly low. This can result in symptoms such as sleep disturbanc­e, hot flashes and night sweats,” says Dr. Khan. A study published in the journal Nature and Science of Sleep in 2018 found that 26 percent of women experience severe symptoms during the menopausal transition, including insomnia.

Going to bed at the same time each night, avoiding caffeine and turning off electronic devices (bye-bye, smartphone) before bedtime helps. “If menopausal symptoms are very significan­t and impact quality of life, low-dose hormone replacemen­t therapy with estrogen and progestero­ne can be used for short periods in women who have a low risk of breast cancer, cardiovasc­ular disease or cerebrovas­cular disease,” says Dr. Khan.

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