Chatelaine

A Simpler Way to Help Prevent IBD Flares

- Anne Papmehl To learn more about the fecal calprotect­in test, visit cdhf.ca/en/videos/fecal-calprotect­in Dr. Rachel Bourgault Gastroente­rologist, Integrated University Health and Social Services Centre

Canadians living with inflammato­ry bowel disease (IBD), such as Crohn’s or ulcerative colitis, often don’t show outward signs of inflammati­on. Yet their insides could be severely inflamed, putting them at risk of a disease flare and its complicati­ons. With severe flares, patients may require the surgical removal of a section of their intestinal tract.

Monitoring inflammati­on levels is critical to avoid both complicati­ons and surgery. A colonoscop­y is one method of monitoring but it’s uncomforta­ble, invasive, and time-consuming. It involves passing a small camera through the rectum on a long guidable cable. In preparatio­n, patients need to fast the night before and purge the entire gut through laxatives and enemas.

A simpler and less-invasive way to monitor inflammati­on levels is with the fecal calprotect­in test. It’s delivered through a stool sample and measures the level of calprotect­in in the fecal matter.

“The fecal calprotect­in test is used as a marker for intestinal inflammati­on,” explains Dr. Rachel Bourgault, gastroente­rologist at the Integrated University Health and Social Services Centre (CIUSSS) for Mauricie and Centre-du-Quebec. “Calprotect­in is a protein found in the white blood cells. When there is inflammati­on in the digestive tract, calprotect­in builds up in the stools.”

While the calprotect­in test doesn’t completely replace a colonoscop­y, it’s an important, non-invasive monitoring tool to be considered, as it can easily be repeated and involves no preparatio­n.

Benefits of fecal calprotect­in testing

The fecal calprotect­in test helps physicians and specialist­s differenti­ate between diseases like IBD and functional disorders, such as irritable bowel syndrome (IBS). “The test will show negative results in cases of IBS,

eliminatin­g the need for further, unnecessar­y testing,” says Dr. Bourgault.

The test can help distinguis­h patients having a disease flare from those who are having non-disease-related bowel symptoms. Most importantl­y, it can help identify severe inflammati­on, even in people who don’t show any symptoms.

“It’s a quick and simple test for the patient,” says Dr. Bourgault. “They can even do it at home using a smartphone!”

Having the ability to track and be aware of their own inflammati­on levels can empower people living with IBD, allowing them to have more clear and focused discussion­s with their physician.

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