Chatelaine

The Future of Eczema Treatment Starts with Healing from the Inside

- Michele Sponagle Dr. Vipul Jain, MB BS, FRCPC Allergy & Clinical Immunology Adjunct Clinical Professor, McMaster University Director, Allergy Research Canada

Atopic dermatitis (AD) is not just skin deep. In a survey conducted among those with moderate to severe forms of this chronic disease by the Eczema Society of Canada, 87 percent of respondent­s said it negatively impacted their daily lives.

Eighty percent reported compromise­d sleep quality and about one-third missed work and important life events.

It’s estimated that up to 17 percent of Canadians have AD — the most common form of eczema, marked by red, itchy, dry skin. Despite its prevalence across the country, it is not well understood and many patients struggle to find effective treatments. Fortunatel­y, new therapies are now available.

To learn more about moderate to severe AD and how it affects the lives of young and old patients alike, Mediaplane­t spoke to Dr. Vipul Jain, an immunologi­st and allergist with practices across Ontario and Melani-Ivy Samson, a 27-year-old Waterloo, ON student who has been living with eczema since she was three-months-old.

Mediaplane­t What are some common misconcept­ions associated with atopic dermatitis?

Dr. Vipul Jain There’s still a belief that it’s contagious, but it’s not something you can catch. It’s caused by an interactio­n of many internal and external factors, like compromise­d skin function, genetics, and the environmen­t. Some think food allergies are responsibl­e, but a causal relationsh­ip has not been establishe­d. Tihis is a complex topic which is still highly debated and more research is needed in this area.

Melani-Ivy Samson Some people think it’s just dry skin and suggest moisturize­rs. They offer advice without knowing the facts, which is frustratin­g.

MP How does it impact patients?

VJ They often suffer work disturbanc­es and a rise in depression. As well, 60 percent experience decreased sexual desire.

MS During flare-ups, I was in pain that was often excruciati­ng — even applying ice packs to my eyes would not alleviate it. I had to bandage my hands and couldn’t go to school. People sometimes stare and it makes me feel self-conscious.

MP What’s new in terms of available treatment options? VJ For resistant eczema or moderate to severe presentati­on, we aren’t just treating eczema from the top down anymore. The most exciting therapies are working from the inside out, utilizing the immune system to heal the skin. For instance, a new monoclonal antibody, administer­ed through a subcutaneo­us injection every two weeks, has been approved for moderate to severe eczema. It’s still very important, however, to continue moisturizi­ng and taking care of the skin.

MP How is this new approach changing lives?

VJ I had a patient who felt hopeless about her appearance. I put her on a newer biologic therapy. While in treatment, her husband touched her arm and she said she experience­d what a normal touch felt like for the first time in her life.

MS I tried everything from UV photothera­py to increasing­ly strong steroid creams, but my condition worsened. Last September, I started getting the new injectable. It has been a complete gamechange­r for me. Within just two weeks, I stopped itching and my skin was healing. When my mom saw me for the first time four months after I began treatment, she burst into tears. She was amazed.

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 ??  ?? Melani-Ivy Samson, a 27-year-old Waterloo, ON student who has been living with eczema since she was three-months-old.
Melani-Ivy Samson, a 27-year-old Waterloo, ON student who has been living with eczema since she was three-months-old.
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