Edmonton Journal

Meeting of the minds

‘Neurons that fire together, wire together,’ says Gunvir Sidhu

- ALEX MIGDAL amigdal@edmontonjo­urnal.com twitter.com/alexem

Local student Gunvir Sidhu gets set for Canadian National Brain Bee.

Ask Gunvir Sidhu about the human brain and his neurons seem to fire at lightning speed.

The Grade 12 student’s initial shy demeanour dissolves when talk turns to the three-pound matter inside the skull. His voice picks up and he grows more boisterous, reciting facts with startling confidence.

“Which drugs trigger abnormal dopamine release in schizophre­nics? That would be amphetamin­es because they promote the release of dopamine. What is the first neurotrans­mitter identified? That’s acetylchol­ine, right?” Right. It’s no surprise, though, considerin­g the Tempo School student is one of 13 students across the country — two from Alberta — competing this weekend in the sixthannua­l Canadian National Brain Bee.

A brain bee? Think of the classic spelling bee setup — a line of students stepping up to a microphone and facing the peril of eliminatio­n — but with a focus on neuroscien­ce: memory, stress, aging, genetics and other related topics.

Sidhu claimed a victory at the Edmonton regional competitio­n in March, which involved memorizing a 50-page neuroscien­ce textbook from front to back.

While most people would get a headache from the painstakin­g process, Sidhu answered every question correctly.

How was the 18-year-old able to pull off such a feat?

“You just read it over and over again. You kind of say stuff out loud, you write it down. If you relate it to some neuroscien­ce, it’s stored in the long-term memory part of your brain. That’s the subconscio­us passage storage memory.

“It’s called heavy learning. Neurons that fire together, wire together.”

It’s certainly the cognitive prowess that Sidhu will need when he squares off against the 12 regional winners — from grades 9 through 12 — at McMaster University in Hamilton, Ont., this weekend.

Organized by the Canadian Institutes of Health Research, competitor­s will have to complete a 50-minute exam, identify multiple structures in the brain and diagnose patients with fake neurologic­al disorders.

Judges will calculate the scores and the top three students will face off with a series of tough questions on the brain.

Although Sidhu says he’s “paranoid” about the other competitor­s, he admits there’s no point in fretting about the competitio­n. As always, he ties his reasoning back to neuroscien­ce: stress will shrink his hippocampu­s — where shortterm memory is converted to long-term memory — and activate the amygdala, which deals with emotions.

“I’m going to get too emotional, so obviously I’m not going to remember all my facts, right? So I’ll just keep my calm and that will be the best way I can get as many questions right as I can.”

That cool confidence likely has to do with Sidhu studying the brain since he was 15, when he first took out a book on the topic at a library. And because of that long-standing affection, Sidhu doesn’t take much stock in winning the $1,500 prize and moving on in September to the Internatio­nal Brain Bee in Vienna, Austria.

“You do things in science for the pleasure of finding them out,” he says. “Maybe when I read the book, instead of just focusing on getting No. 1, I focus on all that it’s teaching me. It talks about a whole bunch of receptors, neurotrans­mitters, things that I’ve never even heard about before.”

Sidhu, who’s set to graduate in two weeks, has scored an internship this summer in a neuroscien­ce laboratory and will be pursuing an honours degree in neuroscien­ce this fall at the University of Alberta.

But despite his achievemen­ts, Sidhu somehow finds a way to turn the conversati­on back to grey matter, and all its mysteries.

“One person compared it to the dark matter in space. The difference is that dark matter is trillions of years away in space. But the brain is inside a skull. You don’t know that much about the brain, just like you don’t know about dark matter. So there’s a ton to learn from stuff like this.”

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 ?? JOHN LUCAS/ EDMONTON JOURNAL ?? Gunvir Sidhu takes part in the annual Canadian National Brain Bee this weekend.
JOHN LUCAS/ EDMONTON JOURNAL Gunvir Sidhu takes part in the annual Canadian National Brain Bee this weekend.

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