Edmonton Journal

Academia urged to tighten reins on fraud

Toronto doctor says it’s time to lock up research miscreants

- MARGARET MUNRO

A leading Toronto doctor has reignited debate over research fraud saying doctors and academics who fudge and fabricate data should be locked up.

Research misconduct can have “huge” impacts, and “it is time to regard such behaviour in the same category as criminal fraud and deal with it accordingl­y,” Dr. Zulfiqar Bhutta, co-director of the Centre for Global Child Health at Toronto’s Hospital for Sick Children, argues in an article published Tuesday in the British Medical Journal.

While not everyone agrees, Bhutta says criminaliz­ation would deter deliberate research fraud, which is “prevalent” and doing “incalculab­le” harm.

He notes how the “fraudulent and discredite­d” work of British researcher Andrew Wakefield has undermined public trust in vaccines around the world. Wakefield was found to have falsified data in a study that linked autism to the measles, mumps and rubella (MMR) vaccine and was barred from practising medicine in the U.K. because of his misconduct.

“Yet he lives a free man in Texas, raking in money from various support groups,” says Bhutta.

Drug companies and their researcher­s have been fined for manipulati­ng data in some high-profile cases, but Bhutta says “the code of conduct for investigat­ing and tackling flagrant research fraud” in the academic world is much less clear.

“In most instances institutio­ns and academic bodies do not follow up on alleged or proved wrongdoing with criminal proceeding­s,” says Bhutta. And even when perpetrato­rs are caught, some of them “claw their way back to active research.”

He points to Korea’s Hwang Woo-suk, who was forced to resign as a professor at Seoul National University after his “landmark” papers on stem cells were found to be fraudulent. Woo-suk has returned to “scientific life” and “written more than 100 scientific publicatio­ns since his fall from grace in 2006, 40 in the past two years alone.”

Bhutta says research fraud should be treated no differentl­y than financial and health-care fraud.

“In cases where deliberate research fraud is proved after thorough investigat­ion, additional deterrence through punitive measures such as criminal proceeding­s should be added to the repertoire of measures available.”

Surveys have found two per cent of all scientists admit to falsifying, fabricatin­g or modifying data at least once, and much of the misconduct is believed to be fuelled by pressure to publish and produce highimpact results. Uncovering misconduct is “all too dependent” on chance detection and whistleblo­wers, says Bhutta.

Dr. Julian Crane, director of a medical research group at the University of Otago in New Zealand, is not convinced calling in the police would “more satisfacto­rily uncover misconduct or prevent harm.”

He says the responsibi­lity should stay with research organizati­ons to reduce misconduct and investigat­e allegation­s.

“Criminaliz­ing research misconduct is a sad, bad, even mad idea that will only undermine the trust that is an essential component of research and requires good governance not criminal investigat­ors,” Crane argues in an article published beside Bhutta’s piece. “It is surely not beyond the expertise of research organizati­ons and their staff to reduce opportunit­ies for misconduct.”

Canada has its share of scientific fraudsters, but universiti­es and research councils often refuse to discuss the cases or reveal the names of the researcher­s involved, even after their misconduct has been substantia­ted.

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Andrew Wakefield

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