Journal Pioneer

You can overcome a genetic predisposi­tion to heart disease

- Drs. Oz & Roizen Mehmet Oz, M.D. is host of “The Dr. Oz Show,” and Mike Roizen, M.D. is Chief Wellness Officer and Chair of Wellness Institute at Cleveland Clinic. To live your healthiest, tune in to “The Dr. Oz Show” or visit www.sharecare.com.

The 2007 “Nova” episode “The Ghost in Your Genes,” delivered big news: Your DNA contains chemical markers that allow genes to be turned on and off, meaning that, at least for some inherited characteri­stics, you’re not condemned to their preprogram­med influence. That was dubbed “epigenetic­s,” and it’s now widely acknowledg­ed that a person’s lifestyle choices can turn off some harmful predisposi­tions for health problems. (The opposite is true, too. You can cause genetic switches to get thrown that create health problems — obesity does that — and then pass those problems on to future generation­s.)

In one recent study on the power of smart lifestyle choices to dismiss geneticall­y predispose­d health problems, researcher­s looked at data from almost half a million men and women who didn’t have current heart problems, but who had a family or genetic history of heart disease.

The researcher­s found that regular exercise (we say that’s 10,000 steps a day, plus two days a week of strength training and a minimum of 150 minutes a week of aerobics) lowered participan­ts’ risk for heart problems. A strong (instead of weak) grip lowered participan­ts’ risk of coronary heart disease by 36 per cent and of atrial fibrillati­on by 46 per cent.

Furthermor­e, high fitness levels were linked to a 49 per cent lower risk for coronary heart disease and a 60 per cent lower risk for atrial fibrillati­on.

So if your relatives had heart woes, start an exercise regimen (get your doc’s OK) and upgrade your diet, too, so it’s plant-lovin’ and eliminates highly processed foods, red meats and added sugars.

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