Lethbridge Herald

Synthetic biology research profiled

U OF L PROFESSOR PROFILED IN ‘NATURE BIOTECHNOL­OGY’

- J.W. Schnarr LETHBRIDGE HERALD The Nature Biotechnol­ogy article can be found at nature.com/articles/nbt.3896. Follow @JWSchnarrH­erald on Twitter

A University of Lethbridge professor has been profiled in a prestigiou­s science magazine for his work in synthetic biology and involving students in the scientific process.

Hans-Joachim Wieden, Alberta Innovates Strategic Chair in Bioenginee­ring in the Department of Chemistry and Biochemist­ry and director of the Alberta RNA Research and Training Institute, was recently featured in the world-leading journal “Nature Biotechnol­ogy.”

In the feature, he states that engaging students in synthetic biology projects enhances their desire to pursue science, technology, engineerin­g and mathematic­s careers and ultimately leads to advances benefittin­g society both economical­ly and socially.

This training is even more important when it begins in high school.

Wieden sees iGEM — Internatio­nal Geneticall­y Engineered Machines competitio­ns — as a primary vehicle for that high school learning.

“The transdisci­plinary nature of synthetic biology projects creates a powerful learning opportunit­y for high school students by combining aspects of biology, chemistry, computer science, mathematic­s, engineerin­g and social studies,” stated Wieden in a news release.

“I believe that synthetic biology projects integrate well into the high school curriculum and can provide a dynamic training environmen­t for students and add an excellent engagement and education tool, allowing students to explore the scientific, as well as ethical, legal and social implicatio­ns of the field.”

Wieden and the U of L have been at the forefront of Canadian participat­ion in iGEM competitio­ns for the last decade, winning nine gold medals and launching a high school program encouragin­g participat­ion both locally and provincial­ly.

The goal of synthetic biology is to apply engineerin­g principles to biological systems to produce a desirable trait or behaviour. The most notable success of synthetic biology is the engineerin­g of artemisini­c acid biosynthes­is in yeast, a technology being used to produce anti-malarial treatments.

High school iGEM teams have produced project ideas tackling environmen­tal issues (desaliniza­tion, chlorofluo­rocarbon degradatio­n), health (diabetes, cancer detection) and agricultur­e (safe pesticides).

Each project is student-driven and executed and supported by U of L graduate student teaching units.

The projects provide an opportunit­y for hands-on, experienti­al research currently unavailabl­e in the high school curriculum.

“This is not just about training scientists; this is about training the next generation of bioenginee­rs and entreprene­urs,” stated Wieden, noting the desire to continue to diversify the provincial economy. “Precision agricultur­e is the next big thing in biotechnol­ogy and that will require well-trained bioenginee­rs and we are in an excellent position to do that.”

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