‘Grey’s Anatomy’ original cast member leaves series

“Grey’s Anatomy” has said goodbye to one of the long-running medical drama’s original cast members — Justin Chambers.

Chambers, who played Alex Karev on the show, left last season after a 15-year run. He leaves only three other actors who have been with the series since the first episode: Ellen Pompeo, James Pickens Jr. and Chandra Wilson. Chambers’ last episode aired Nov. 14. Chambers said in a statement he has “hoped to diversify my acting roles and career choices. And, as I turn 50 and am blessed with my remarkable, supportive wife and five wonderful children, now is that time.”