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Stem Cell Donors Could Be Someone’s Hope for Life

- Randi Druzin Dr. Heidi Elmoazzen Director, Stem Cells, Canadian Blood Services

Every year, hundreds of Canadian patients need life-saving stem cell transplant­s, and most rely on the generosity of an unrelated donor. Found primarily in umbilical cord blood, peripheral circulatin­g blood, and bone marrow; blood-forming stem cells are used to treat more than 80 diseases and disorders, such as leukemia, lymphoma, aplastic anemia, and sickle cell disease.

To significan­tly increase the odds of finding a matching stem cell donor for patients, the Canadian Blood Services Stem Cell Registry — the public registry responsibl­e for recruiting and finding healthy, committed volunteer donors — belongs to an internatio­nal network of registries to match potential donors and recipients around the world. For every patient who finds a match among their family, three will rely on a total stranger’s generous donation of life-saving stem cells. With almost 450,000 registrant­s and access to more than 35 million potential stem cell donors on this network, the odds of finding a match are much, much higher.

“If you donate cord blood or join the stem cell registry, you may save a life,” says Dr. Heidi Elmoazzen, Director of Stem Cells at Canadian Blood Services. It’s that simple. Yet, about half the registrant­s contacted to launch the actual donation process decline to proceed with the donation — a potentiall­y devastatin­g experience for the patient. This is why registrant­s are often reminded that joining the registry is a long-term commitment — it could be months or even years before they may be called to donate.

Patients are more likely to find a donor from within their own ancestral group. Also, patients of diverse ethnic or mixed-race background­s face a much steeper hill when searching for a stem cell match. This is why the stem cell registry specifical­ly targets potential donors from diverse ethnic background­s who are also optimal donors — males aged 17 to 35.

Donating cord blood — the blood that remains in the umbilical cord and placenta after the birth of a healthy baby — is another way to help patients. Canadian Blood Services’ Cord Blood Bank launched in 2013 to provide expectant mothers the opportunit­y to donate to a national public cord blood bank at four hospital collection sites in Ottawa, Brampton, Edmonton, and Vancouver. Joining the Canadian Blood Services Stem Cell Registry involves a simple cheek swab and the understand­ing that this could be a long-term commitment. For pregnant moms living in a city with a designated cord blood collection hospital, you and your tiny hero could save lives by joining Canada’s Lifeline.

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