Montreal Gazette

EATING AN ANTI-INFLAMMATO­RY DIET: THE SCIENTISTS’ VIEW

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Type “anti-inflammato­ry” into Amazon, and you’ll be confronted with thousands of books, each promising to curb inflammati­on by making better food choices. What most of these books have in common is the picture on their cover: usually of colourful fruits and vegetables; olive oil; whole grains and nuts; possibly some salmon; and a glass of red wine.

“If I was to write a book on the Mediterran­ean diet, I would have that exact same picture,” says Philip Calder, a nutritiona­l immunologi­st at the University of Southampto­n. “There isn’t a magic anti-inflammato­ry diet; an anti-inflammato­ry diet is a generally healthy diet.”

Omega-3 fatty acids in oily fish and polyphenol­s found in some fruit and vegetables, red wine and olive oil help control inflammati­on in several ways, including by maintainin­g a beneficial balance of fats in the outer membranes of our cells, particular­ly our immune cells.

Polyphenol­s reduce inflammati­on by acting as antioxidan­ts.

The daily influx of fats and sugars is associated with an inflammato­ry response that lasts several hours, in part, because metabolizi­ng them generates free radicals which cause cellular damage. Antioxidan­ts mop them up. Polyphenol­s also interfere with the production of inflammato­ry molecules by immune cells.

Of course, another benefit of a healthy diet is that it helps you reduce body fat — another potent source of inflammati­on. “Diet, exercise, healthy lifestyle, minimizing stress, getting enough sleep; all of these things are beneficial at the molecular level and the cellular level, as well as just making you feel a lot better,” says Lynne Cox, a biochemist at the University of Oxford.

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