National Post (National Edition)

Study shows impact of contact on B.C. natives

- The Canadian Press

GENETIC CHANGES

the gene was involved in immunity, we can infer that maybe it was adapted to the pathogens in their ancient environmen­ts.”

However, Malhi and his team found that the occurrence of that DNA began to fall in human remains from about the time of European contact. Most modern members of those communitie­s no longer have that DNA, Malhi said.

“After Europeans arrived and changed the environmen­t, worked. He points out oral history from those communitie­s tells of massive disease outbreaks at about the time of contact.

“We don’t know what the mechanism is. We can infer there’s a possibilit­y that it might be associated with smallpox.”

First Nations were also being affected by warfare and massive social and cultural change at the same time.

It’s hard to estimate exactly how much life was lost. Malhi’s research indicates that between 125 and 225 years ago, those First Nations lost about 57 per cent of their genetic diversity.

“It suggests a huge drop in population.”

Malhi’s research was conducted with the full cooperatio­n of the two First Nations involved. Two members of those communitie­s travelled back to the research lab at the university to observe the handling and study of the human remains, which consisted mostly of materials such as bone and teeth fragments.

The results have also been shared with the communitie­s.

Malhi is currently extending his work to look at the genetic consequenc­es of European contact on other First Nations in Alaska, California and Mexico.

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