Ottawa Citizen

How old can you get?

DON’T EXPECT OUR LIFESPANS TO GET ANY LONGER

- COLBY COSH National Post ccosh@postmedia.com Twitter.com/colbycosh

SHE IS NOT MERELY THE ONLY VERIFIED 122-YEAR-OLD IN HUMAN HISTORY; SHE IS STILL ITS ONLY 121-YEAR-OLD AND ITS ONLY 120-YEAR-OLD. — COLUMNIST COLBY COSH

Do you remember Jeanne Calment, the French woman who lived to be 122 years old? The Arlésienne died in 1997; as the person who lived to the greatest verifiable age, she enjoyed an unusually long time in the media spotlight as the senior member of our species. She is remembered for having sold pencil crayons to Vincent van Gogh, whom she remembered as “dirty” and “disagreeab­le,” and for having smoked cigarettes for 96 years, surely a record in itself.

I am sure you probably do remember Jeanne Calment if you are old enough. Stories of what gerontolog­ists call “supercente­narians” — people who breeze past their 110th birthdays — have been clickbait since before we called it that. Today’s quasioffic­ial oldest living person is Emma Morano, a chatty, ambulatory Italian scheduled to turn 117 on Nov. 29. There are, as always, other contenders, whose families insist they are older. But for now, Morano is the last identifiab­le human alive who was definitely born in the 1800s.

Since Jeanne Calment died, supercente­narian research, once left mostly up to the Guinness Book of Records, has gained an organized framework, much as baseball history did when publishers started compiling statistica­l encycloped­ias. There are now multiple internatio­nal groups working to collect, validate and study extreme lifespans. If you are an enthusiast of this subject, this has gradually turned Calment from a sly, wonderful curiosity, into something more sinister — a figure standing at the gates of the afterlife, taunting us.

It would be natural to expect her lifespan record to have been challenged and beaten sometime in the last two decades. Instead, she remains supreme, a Beamonesqu­e outlier. She is not merely the only verified 122-year-old in human history; she is still its only 121-year-old and its only 120-year-old.

The internatio­nal Gerontolog­y Research Group (GLG), founded at the University of California, Los Angeles, and now a worldwide network of pro-am age detectives, maintains a table of all confirmed supercente­narians.

As often happens with mass death data of any kind, it is upsettingl­y regular in shape. The most recent version of the table, updated on New Year’s Day 2014, lists 764 people confirmed from good public records and other corroborat­ing informatio­n to have died at the age of 110. At 111, the number drops to a little more than half that: 416 people. At 112, the number drops again by a bit less than half. By the time we reach age 117, there are only two people. There is one 119-year-old in the table, Sarah (Clark) Knauss (1880-1999) of Pennsylvan­ia. Beyond that, there’s only Jeanne Calment, defying all challenger­s.

A new study in Nature magazine, performed by number-crunchers from the Albert Einstein College of Medicine in New York, delves deeper into mortality statistics and confirms the troubling picture of a possible inherent, or at least very intractabl­e, limit to human lifespan.

The overall human life expectancy — the mean amount of time an average person may expect to live — increased rapidly throughout the past century, with downturns that coincided with global wars. It is still rising impressive­ly. The largest gains were, at first, accounted for by public-health improvemen­ts like plumbing and antibiotic­s, which had their biggest impact among babies and children. Then, medicine in the developed countries started solving the more complex ills of the middle-aged and elderly.

The Einstein College doctors made a plot of the age at which people in each calendar year experience­d the biggest gains in life expectancy. They document that in the countries with the best health care and the best mortality data, that age is now well above 100. In Canada — as well as Denmark, Japan, Sweden and other developed countries — the line marking the age of greatest survival benefit plateaued around 1980 at about 104 for both sexes, and it is stuck there.

Going forward, countries like ours can expect to have many more centenaria­ns, and they will be in ever better health. But so far, we have not succeeded in increasing the life expectancy of supercente­narians to any significan­t degree. A separate analysis, taken from the GLG’s data and other similar data sets, suggests that the highest attainable age is not rising over time and may, if anything, be in decline.

These inferences are taken from fairly small samples, and the dismal message is obviously subject to a sudden breakthrou­gh in the understand­ing of human aging. But that is the whole point: such breakthrou­ghs have been arguably quite late in arriving. The very old still often die without an attributab­le cause, as Calment did.

Most gerontolog­ists are now pretty sure that human cells or genes do not harbour evolutiona­ry switches, “deliberate­ly” installed by nature, that shut us off to make room for descendant­s. But they are still not collective­ly certain whether aging is, at the extremes, a matter of entropy — of the natural tendency for organized matter to fall apart — or of concealed diseases that might be treatable. Of course, I still personally hope to look back on that sentence in the year 2500 and laugh …

 ?? THE ASSOCIATED PRESS FILES ?? Jeanne Calment, who died in 1997 at the age of 122, was believed to be the world’s oldest person. Data analysis on aging suggests that the highest attainable age is no longer rising over time and may be in decline, Colby Cosh writes.
THE ASSOCIATED PRESS FILES Jeanne Calment, who died in 1997 at the age of 122, was believed to be the world’s oldest person. Data analysis on aging suggests that the highest attainable age is no longer rising over time and may be in decline, Colby Cosh writes.
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