Ottawa Citizen

Tried and true: Here’s what works and what doesn’t work

- JOANNE LAUCIUS

What are safe and effective products to protect yourself against this coronaviru­s?

We turned to Jason Kindrachuk, a medical microbiolo­gist who is the Canada Research Chair in molecular Pathogenes­is of Emerging and Re-Emerging Viruses at the University of Manitoba, where he leads a team of scientists researchin­g the biological mechanisms of emerging and re-emerging viruses. They have a lab to clean, so they should know what works.

“With this coronaviru­s, there are nuances we don’t understand yet,” Kindrachuk said. “I understand why people are nervous.”

Still, he says we’re past the point of containmen­t and at the point of mitigation. “We have to go back to things that are tried and true, and that work well. It’s a fairly limited list. We need to use things that work.”

Here’s what works and what doesn’t work:

Soap and water: The top defence mechanism is good hygiene, says Kindrachuk. Viruses are extremely vulnerable to detergent because they are contained inside a fatty protective membrane that is detergent soluble. Soap breaks apart the outer layer and the virus is split apart. Liquid soap works well on surfaces because of the ease of handling, and bar soap works well on skin.

“As long as you get a good buildup of suds, you will be able to inactivate anything that’s on the surface,” Kindrachuk says.

Health Canada recommends washing your hands often with soap and water for at least 20 seconds, especially after using the washroom and when preparing food. Use alcohol-based hand sanitizer if soap and water aren’t available.

Bleach and water: Health Canada recommends cleaning high-touch surfaces frequently with regular household cleaners or diluted bleach. This includes toys, toilets, phones, electronic­s, door handles, bedside tables and television remotes.

Diluted bleach is very effective in the right proportion­s: A solution of 10 per cent bleach to 90 per cent water will render inactive just about anything. “It’s hell on surfaces, but it works really, really well,” Kindrachuk said.

The active ingredient in household bleach is sodium hypochlori­te and normally runs in the range of three to six per cent, he said. This should be listed on the ingredient­s section of the label. While we don’t know the specific concentrat­ion needed to inactivate this coronaviru­s, data from other coronaviru­ses, including SARS-CoV, suggests 0.1 to 0.5 per cent sodium hypochlori­te.

A one-in-10 dilution of household bleach would provide a solution in the range of 0.3 to 0.6 per cent for disinfecti­ng. “We use this on stainless steel surfaces in our lab, but follow that up with our 70-per-cent ethanol solution due to the potential damage of bleach to the surface,” he said but added: “This is definitely overkill for household cleaning given that bleach is something you don’t want to have copious amounts of on your skin or sitting around on surfaces.”

And, of course, it relies on people making accurate dilutions in their homes. Your best bet is still to use liquid dishwashin­g soap to clean your surfaces. “It will do the trick,” Kindrachuk said.

Alcohol: Most viruses are susceptibl­e to alcohol with a concentrat­ion of at least 60 per cent. Kindrachuk’s lab uses 70-per-cent ethanol. “The European Centre for Disease Prevention and Control has an excellent document on this. They recommend 70-per-cent ethanol or 50-per-cent isopropran­ol, specifical­ly for coronaviru­ses. This range of alcohol concentrat­ions also worked well for non-enveloped viruses like noroviruse­s, which are more stable than their enveloped counterpar­ts.”

Hand sanitizer: The CDC recommends preparatio­ns with 60 per cent or higher alcohol content. Be sure to look at the ingredient list when purchasing hand sanitizer. Still, liquid soap is far superior and the better investment, Kindrachuk said. He points out that sanitizers only work on surfaces that are already clean. Soap and water will cut through oil and grease on skin. Do-it-yourself hand sanitizer: There are a number of online recipes suggesting that you can make your own hand sanitizer using rubbing alcohol with aloe vera gel to reduce skin irritation. This is one case where it’s better not to get all artisanal about it. Kindrachuk suggests that if you’re not mixing it in the right proportion­s, your product may be ineffectiv­e.

And for heaven’s sake, don’t make your own hand sanitizer with vodka.

Last week, Tito’s Handmade vodka asked consumers not to use its product to make hand sanitizer, citing the U.S. Centers for Disease Control (CDC). “Per the CDC, hand sanitizer needs to contain at least 60 per cent alcohol,” said Tito’s in a tweet on Thursday. “Tito’s Handmade Vodka is 40 per cent alcohol, and therefore does not meet the current recommenda­tion of the CDC.”

How long can this virus remain active on surfaces? That’s unclear, although some reports have suggested a couple of days. However, when tests are done in a lab, they are done under very specific conditions that don’t necessaril­y mimic traditiona­l surfaces or environmen­tal conditions that one would encounter on their daily commutes and so forth, Kindrachuk points out.

We still don’t know how much of the virus would be required to affect someone — if you touch your finger to a surface and touch your face, for example. The presence of a virus does not equate to infection. This is called the efficiency of transmissi­on.

Cold temperatur­es: “Viruses do not last that long outside. Viruses don’t last long in cold environmen­ts,” Ontario’s Dr. Chief Medical Officer of Health Dr. David Williams said at a news conference earlier this month.

It is true that viruses are inactivate­d in sub-zero temperatur­es, Kindrachuk said. They freeze and the virus’s outer layer breaks apart.

On the other hand, some others have suggested that a mild spring will also do the trick — a virus’s fatty protective covering disintegra­tes when it’s warm. But Kindrachuk warns it’s too early to say if this is true with this coronaviru­s. While heat also inactivate­s viruses, increases in ambient outdoor temperatur­es are not an accurate predictor that viruses have been killed.

While UV light can inactivate different pathogens, the effectiven­ess of UV lights — or exposure to sunlight — also can’t be guaranteed in this case.

Witch-hazel, tea tree oil and other natural products: Many natural products have antimicrob­ial properties, but in this case, it’s unclear what concentrat­ion is needed. “These products have not been rigorously tested for their ability to inactivate a broad range of viruses, thus we cannot use them under biosafety standards,” Kindrachuk said.

Vinegar: Acetic acid has antimicrob­ial properties, but when it comes to this virus, there’s also no establishe­d concentrat­ion. “There was a study a few years ago that looked at the ability of diluted malt vinegar to inactivate H1N1 influenza virus. They showed that 10 per cent and 50 per cent solutions of this could inactivate the virus. However, there is no clear data for coronaviru­ses or a more broad range of viruses.”

How often should you clean? “This is something that is definitely up to the individual. If there are cases in the community, it is something to consider. My suggestion would be to keep control of the things that you can — for example your own hands and skin. If you touch a surface like a touchpad in an elevator, for example, this is something you can control by continuing to avoid touching your face in public with unclean hands, having a hand sanitizer with you and/or washing your hands when possible.” jlaucius@postmedia.com

With this coronaviru­s, there are nuances we don’t understand yet. I understand why people are nervous.. JASON KINDRaCHUK, a microbiolo­gist. SEE STORY, THIS PAGE

 ??  ?? Wash hands with soap and water is the best defence against coronaviru­s, says medical microbiolo­gist Jason Kindrachuk.
Wash hands with soap and water is the best defence against coronaviru­s, says medical microbiolo­gist Jason Kindrachuk.
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GETTY ?? Natural products like witch and tea tree oil may have antimicrob­ial properties, but their effectiven­ess against viruses has not been tested.
IMAGES/ISTOCKPHOT­O GETTY Natural products like witch and tea tree oil may have antimicrob­ial properties, but their effectiven­ess against viruses has not been tested.
 ?? REUTERS ?? The CDC says hand sanitizer should have 60 per cent or higher alcohol content.
REUTERS The CDC says hand sanitizer should have 60 per cent or higher alcohol content.
 ??  ?? A solution of 10 per cent bleach to 90 per cent water is recommende­d for cleaning surfaces.
A solution of 10 per cent bleach to 90 per cent water is recommende­d for cleaning surfaces.
 ?? CHRIS MIKULA ?? There is no approved concentrat­ion of vinegar as an anti-virus measure.
CHRIS MIKULA There is no approved concentrat­ion of vinegar as an anti-virus measure.

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