Book a room at the Six Senses Douro Valley. The hotel is housed in what was once the Quinta de Vale Abraão, a 19th-century manor overlooking sloping vineyards and the gently curving Douro River. But that makes it sound quainter than it is. The first Six Senses resort in Europe, the hotel has been renovated in the modern Portuguese style, complete with a stunning linear addition for the indoor pool and spa. The hotel’s restaurant serves locally inspired dishes, and the wine list is — no surprise — extensive. The Enomatic, a highly curated wine vending machine, ensures you’re always with a glass in hand. Three hours from Lisbon, the Douro Valley is a UNESCO World Heritage Site, and the world’s oldest dedicated wine region. AKA: all the reason you need to visit Portugal.