The Daily Courier

Weather snarls vaccine delivery

U.S. snow snarls vaccine delivery; minister fears variants in First Nations

- By LAUREN KRUGEL

As snowy weather south of the border snarls vaccine deliveries to Canada, Indigenous Services Minister Marc Miller says he fears the prospect of highly transmissi­ble COVID-19 variants taking hold in First Nations communitie­s.

"I don't think I can be any more concerned," Miller said Wednesday in Ottawa, noting several socio-economic factors put Indigenous people more at risk from the virus.

Miller said that as of Tuesday there had been more than 19,000 confirmed COVID19 cases on First Nations reserves, nearly 1,400 of which were active.

Active cases are one-quarter what they were a month ago, but Miller said "these numbers continue to be alarming."

He said the Prairie provinces, in particular, have had "really scary spikes."

"It is no secret that the opening up of the economies at the end of the summer created that catalyst," Miller said.

"The science is showing that we're still very much at risk as a country and none more so than Indigenous communitie­s, who have really, really fought and continue to fight overwhelmi­ng odds.

"The best way to see a third wave is to ignore the science."

New recommenda­tions from the National Advisory Committee this week say all adults in Indigenous communitie­s should receive a COVID-19 vaccine in the second stage of the immunizati­on campaign to start this spring.

Miller said vaccinatio­ns have started in 400 Indigenous communitie­s. More than 83,000 doses had been administer­ed as of Tuesday.

Shipping company UPS temporaril­y closed its operations in Kentucky earlier this week after a big snowfall, which delayed a shipment of Canada-bound vaccine. Canada's doses of the PfizerBioN­Tech vaccine are made in Belgium, but are routed through the UPS air hub in Kentucky.

Heath Canada said provinces could expect to receive shipments of the PfizerBioN­Tech product at least a day behind schedule, but all 400,000 doses should be in Canada by Friday.

Meanwhile, Quebec's health minister announced the province is making rapid COVID-19 tests available to private companies to reduce workplace outbreaks. The province is among those to have been criticized for its slow rollout of rapid tests, which provide faster results than standard polymerase chain reaction, or PCR, tests.

Also in Quebec, new modelling released by the province suggests a more contagious COVID-19 variant could be the dominant strain circulatin­g in Montreal by next month.

Quebec added 14 more deaths from past dates, but no new ones, in its update Wednesday. It reported 800 new infections and five fewer COVID-19 patients in hospital than a day earlier.

Ontario recorded 847 new infections, along with 10 more deaths and 23 fewer people in hospital than the day before.

In Newfoundla­nd and Labrador, which is under strict measures to curb the spread of the novel coronaviru­s, there were 44 new confirmed cases and 21 presumptiv­e ones.

Dr. Janice Fitzgerald, chief medical officer of health, said there were 338 reported active cases in the province, and thousands of people were coming forward for testing.

Manitoba had 75 new cases and one additional death. The province also said 27 tickets were issued last week to people accused of breaking public health orders -- more than half of which were for not wearing a mask in an indoor public place.

OTTAWA -- Health Canada is not yet ready to make a decision about approving the COVID-19 vaccine from AstraZenec­a, more than two weeks after it signalled the ruling could be imminent.

The World Health Organizati­on gave its seal of approval to AstraZenec­a Monday, and if Health Canada follows suit, almost 500,000 doses could be shipped to Canada in March through the global vaccine-sharing program known as COVAX.

But Health Canada is still having a back and forth with the British-based company on the clinical data behind the vaccine.

“Health Canada continues to work with AstraZenec­a to receive the informatio­n needed to complete its review,” said Kathleen Marriner, a spokeswoma­n for the department.

While it was expected AstraZenec­a would be the third vaccine approved in Canada, it is now on the verge of being surpassed by Johnson and Johnson.

The Food and Drug Administra­tion in the United States is meeting to decide on approving that vaccine Feb. 26, and the European Medicines Agency expects to make a decision in early March. Health Canada has been collaborat­ing with both on vaccine reviews for COVID-19.

“While each country makes independen­t decisions in keeping with its own processes, Health Canada is on similar timelines with the decisions of our key regulatory partners, once all of the data needed to make a decision has been received and reviewed,” Marriner said.

In addition to getting AstraZenec­a doses from COVAX, Canada bought 20 million directly from the company, and 10 million doses from Johnson and Johnson.

Deliveries of both would begin this spring if they get approved.

Nobody has yet approved Johnson and Johnson’s vaccine, but AstraZenec­a has been authorized by more than two dozen jurisdicti­ons. Only Pfizer-BioNTech’s COVID-19 vaccine has been approved in more places.

The FDA is waiting for a clinical trial of AstraZenec­a’s vaccine in the U.S. to be finished, but Europe authorized it Jan. 29.

That decision prompted Health Canada to change its language from saying the AstraZenec­a review was “ongoing”, to saying a decision would be announced “in the coming days.”

On Feb. 9, Health Canada’s chief medical adviser Dr. Supriya Sharma said the review was in “the final stages,” just awaiting some final “back and forth” to finalize the rules for how the vaccine is to be used and on whom.

A week later, and there is still no sign that decision is imminent.

Sharma said the vaccine has been complicate­d to review because of a number of factors, including a mix-up in how big the doses were during the clinical trial and questions about how effective it is against new variants of the virus that causes COVID-19.

South Africa last week stopped using AstraZenec­a’s vaccine completely, fearing it wasn’t doing enough to prevent people from getting sick from the B.1.351 variant that now dominates infections there.

The company was also challenged about what data it had on the effect the vaccine had in older adults, with fears not enough people over 65 were exposed to the virus after getting the vaccine to be certain of how well it protected them. Antibody tests, however, showed similar immune responses in people over 65 as was seen in younger people.

Many European countries, including France and Germany, authorized it only for use on people younger than 65. Several other countries have approved it for all age groups, including the United Kingdom, which has leaned heavily on the AstraZenec­a vaccine to get at least one dose to nearly 16 million people in just two months.

The World Health Organizati­on’s approval this week is also for everyone over the age of 18.

The age decision is one factor that has been of concern to Health Canada, Sharma noted last week.

Canada has been falling down the list of countries in terms of how many people have been vaccinated, largely as deliveries of both vaccines approved here slowed in mid-January.

As of Wednesday afternoon, almost one million people have received at least one dose, with 335,000 of them having received the second needed dose. But the U.K. has vaccinated almost one in four people, and the United States about one in six.

Procuremen­t Minister Anita Anand told a Canadian Chamber of Commerce event Wednesday that the delays did slow things down but that the worst is over.

“I think what you are going to see is the story on vaccinatio­ns is still being written,” she said. “Canada is going to see a very, very steep incline in the next weeks and months ahead.”

Pfizer-BioNTech’s delivery delays are now over, with 403,000 doses arriving this week and plans to ship three million over the next six weeks. Moderna intends to ship almost 1.5 million doses before the end of March.

Together the two companies are to ship 20.8 million doses in the spring and more than 50 million in the summer.

Pfizer’s deliveries did face another slight delay Monday, but this time weather was the culprit. A snowstorm in Louisville, Ky., prompted UPS to close its air hub there, pushing Canada’s deliveries back 24 to 36 hours.

Canada’s doses come from Belgium but are shipped via Kentucky. Health Canada says the shipments should all be in Canada by Friday.

 ?? The Associated Press ?? Michelle Terrazas tosses a log as people wait in line Wednesday in Dallas. With a long line of folks waiting in their vehicles after snow and ice collapsed the Texas power grid, groups of 13 were allowed six minutes to load as much wood as they could carry from a recycling centre that started selling firewood to help people stay warm.
The Associated Press Michelle Terrazas tosses a log as people wait in line Wednesday in Dallas. With a long line of folks waiting in their vehicles after snow and ice collapsed the Texas power grid, groups of 13 were allowed six minutes to load as much wood as they could carry from a recycling centre that started selling firewood to help people stay warm.
 ?? The Associated Press ?? Medical staff display a container of AstraZenec­a vaccine in Bucharest, Romania, on Monday. The Canadian government has yet to approve the vaccine.
The Associated Press Medical staff display a container of AstraZenec­a vaccine in Bucharest, Romania, on Monday. The Canadian government has yet to approve the vaccine.

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