The Hamilton Spectator

Drug proves effective against virus

Treatment offers hope as U.S. economic output continues to shrink

- MARTIN CRUTSINGER, MARILYNN MARCHIONE AND PAT EATON-ROBB

Scientists on Wednesday announced the first effective treatment against the coronaviru­s — an experiment­al drug that can speed the recovery of COVID-19 patients — in a major medical advance that came as the economic gloom caused by the scourge deepened in the U.S. and Europe.

The U.S. government said it is working to make the antiviral medication remdesivir available to patients as quickly as possible.

“What it has proven is that a drug can block this virus,” said Dr. Anthony Fauci, the government’s top infectious-disease expert. “This will be the standard of care.”

Stocks surged around the world on the news, with the Dow Jones industrial average gaining more than 530 points on the day, or over two per cent.

Still, word of the new drug came as the U.S. government reported that American economic output is shrivellin­g in the biggest and fastest collapse since the Depression. The virus has killed over 220,000 people worldwide, including more than 60,000 confirmed deaths in the U.S., and led to lockdowns and other restrictio­ns that have closed factories and other businesses around the globe.

The U.S. said its gross domestic product, or output of goods and services, shrank at an annual rate of 4.8 per cent in the January-March period, the sharpest quarterly drop since the global financial meltdown of more than a decade ago.

And the worst is yet to come: the Congressio­nal Budget Office has estimated that the GDP of the world’s biggest economy will plunge at a 40 per cent annual rate during the threemonth period that ends in June.

The latest figures on people applying for unemployme­nt benefits in the U.S. come out Thursday, with economists estimating perhaps one in six American workers, or nearly 30 million people, have lost their jobs over the past six weeks.

The U.S. unemployme­nt rate for April will be released at the end of next week, and economists have said it could range as high as 20 per cent — a level last seen during the Depression.

Mario Franco, who worked at a McDonald’s at a rest stop along Interstate 95 in Darien, Connecticu­t, for 26 years, rising to night manager in charge of the kitchen staff, was laid off in late March. The 50-year-old said he has little savings and now relies on a food bank and union donations.

“They didn’t give us any notice,” he said through an interprete­r.

“They didn’t tell us about it. Just suddenly the night shift ended and that was it. There was no more work.”

Amid the economic carnage, President Donald Trump was pushing to reopen the country, allowing federal social distancing guidelines to expire Thursday and even saying he plans to travel to Arizona next week.

Trump laid out plans for returning to pre-virus normalcy despite doctors’ warnings that the country will need to embrace extended social distancing and mask-wearing.

Confirmed infections globally reached about 3.2 million, including one million in the U.S., according to a tally by Johns Hopkins University. The true numbers of deaths and infections are believed to be much higher because of limited testing, difference­s in counting the dead and concealmen­t by some government­s.

California-based biotech company Gilead Sciences and the U.S. government reported that in a major study, remdesivir shortened the time it takes for COVID-19 patients to recover by four days on average — from 15 days to 11. Also, a trend toward fewer deaths was seen among those on the drug, Fauci said.

The study was run by the U.S. National Institutes of Health and involved 1,063 hospitaliz­ed coronaviru­s patients around the world.

An effective treatment could have a profound effect on the outbreak, since a vaccine is probably a year or more away. Economic damage, meanwhile, is piling up around the world.

The United Nations’ main labour body predicted the world will lose the equivalent of about 305 million full-time jobs in the second quarter.

 ?? TONY DEJAK THE ASSOCIATED PRESS ?? A woman walks her dog past a closed business on Wednesday in Chagrin Falls, Ohio. The U.S. economy shrank at an annual rate of 4.8 per cent in the January-March period.
TONY DEJAK THE ASSOCIATED PRESS A woman walks her dog past a closed business on Wednesday in Chagrin Falls, Ohio. The U.S. economy shrank at an annual rate of 4.8 per cent in the January-March period.

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