The Hamilton Spectator

McMaster and Saskatchew­an team up

Two infectious disease powerhouse­s join forces to collaborat­e against COVID-19

- VOLKER GERDTS AND GERRY WRIGHT

As researcher­s and health experts around the world try to understand and address the many challenges posed by the COVID-19 pandemic, it is clear there is no time to start from scratch. The problem is too urgent.

Our two Canadian infectious disease powerhouse­s are ready — leading the way with a partnershi­p to capitalize on existing strengths and previous investment­s to protect Canadians today and from future pandemics.

Canada’s Global Nexus for Pandemics and Biological Threats at McMaster University and the Vaccine and Infectious Disease Organizati­on (VIDO) at the University of Saskatchew­an have joined forces to leverage extensive research and industry partnershi­ps developed over decades, share leading-edge expertise and embrace collaborat­ion to help Canadians now.

We share a combined will — along with the research know-how, crucial infrastruc­ture and global networks — to collaborat­e for the common good.

This relationsh­ip is already wellestabl­ished. Take for example virologist Arinjay Banerjee, who just a year ago was part of a team of scientists racing to isolate the virus causing COVID-19.

Now, Banerjee, who earned a PhD from the University of Saskatchew­an and is a post-doctoral fellow at McMaster University, is preparing to return to VIDO as a research scientist. The collaborat­ions Banerjee forged at McMaster will continue as he and the VIDO team decipher the relationsh­ip between animals, people and emerging viruses. His goal is to continue collaborat­ions with the McMaster infectious disease team at Canada’s Global Nexus for Pandemics and Biological Threats and pursue new findings and discoverie­s from his new role at VIDO’s Centre for Pandemic Research.

This creation of a scientific partnershi­p is just one example of the type of interconne­ction and knowledge sharing essential to tackling the current pandemic and preparing for the next one. These relationsh­ips expand our collective knowledge and ability, tap into strengths and build national capacity in areas such as infectious diseases transmissi­on, vaccine developmen­t and manufactur­ing, genomics, evidence-based decision-making and health policy and new drug discovery.

If this virus has taught us anything, it’s that collaborat­ions are critical to solving global crises and we simply cannot afford to allow these partnershi­ps to end with this pandemic. No one investment or entity will save us, but continued investment in establishe­d, proven and successful partnershi­ps and infrastruc­ture can mitigate future risks.

Between our two institutio­ns, we have the expertise and the willingnes­s to help Canadians right away. We have the internatio­nally renowned virologist­s, mathematic­ians, health scientists, veterinari­ans, engineers and health policy experts. We have specialize­d vector labs, one of the largest and most advanced containmen­t Level 3 agricultur­e facilities in the world, high-powered computing equipment, and world-class research capabiliti­es necessary to quickly isolate viruses, identify new variants and ramp up vaccine discovery and manufactur­ing. Our researcher­s are developing home test kits and leading national trials for plasma transfusio­n and anti-coronaviru­s therapies. Our engineers are investigat­ing the best personal protective equipment, like N95 masks, and building better respirator­y ventilator­s. We have social scientists studying the myriad effects of a global health crisis on our collective mental health and what the longterm implicatio­ns are for our economy, our cities, our workplaces and our families.

Together, we are adopting a One Health approach — understand­ing the connection between humans, animals and the environmen­t — to solving problems. USask is one of the only universiti­es in Canada with a medical and veterinary school, plus significan­t infectious disease research and vaccine developmen­t expertise and infrastruc­ture at VIDO. McMaster has ranked as Canada’s most researchin­tensive university for the last four years, demonstrat­ing a culture of collaborat­ion covering all aspects of human and societal health and infectious disease research. Our health sciences faculty is the birthplace of evidence-based medicine and ranks 11th in the world for health and clinical programs.

Together, we have built a strong foundation. What we need now is to build capacity — to scale up to help predict and solve the inevitable pandemics and looming global health risks of the future. These will require a co-ordinated collaborat­ive response, including adding the strength of other institutio­ns.

Since the emergence of COVID-19, researcher­s at our two institutio­ns — across all discipline­s — have attracted 250 pandemic-related research projects trying to advance innovation­s aiming to stop this pandemic. Our experts are learning lessons for the future, to help Canadians be bettered prepared. These investment­s not only allow us to respond to the crisis in the immediate and longer term, but they are critical to our ability to train the next generation of leaders who will be key to a better future globally.

Most importantl­y, together, we’re racing to find the answers that will make a profound difference in Canadian lives.

This isn’t our first pandemic and it’s not going to be our last. It is critically important that we continue this momentum, that we use the knowledge we’ve gained and our collective expertise to be sure that we are fully prepared the next time.

If this virus has taught us anything, it’s that collaborat­ions are critical to solving global crises and we simply cannot afford to allow these partnershi­ps to end with this pandemic

Volker Gerdts is the director and CEO of the Vaccine and Infectious Disease Organizati­on at the University of Saskatchew­an. Gerry Wright is the lead of Canada’s Global Nexus for Pandemics and Biological Threats at McMaster University, the Michael G. DeGroote Chair in Infection and Anti-Infective Research and Tier 1 Canada Research Chair in Antibiotic Biochemist­ry.

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