Breast Can­cer Aware­ness Month - Oc­to­ber

The Miracle - - Front Page - By Em­blem Cannabis

Dev­as­tat­ing To All Of Those Who Are Di­ag­nosed Or Have A Loved One Di­ag­nosed, breast can­cer is the most com­mon type of can­cer and the sec­ond lead­ing cause of can­cer-re­lated death in Cana­dian women (lung can­cer is first). For Breast Can­cer Aware­ness Month, we want to do our part to spread the word on what ex­actly breast can­cer is, who gets it and why reg­u­lar screen­ings for early de­tec­tion is key. What is breast can­cer? Broadly termed, can­cer is a class of dis­eases char­ac­ter­ized by the ap­pear­ance of ab­nor­mal, mu­tated cells that grow, mul­ti­ply and in­vade healthy cells, form­ing can­cer­ous (ma­lig­nant) tu­mours. Specif­i­cally, with breast can­cer, these tu­mours can be felt within the breast tis­sue as hard lumps. They can also be spot­ted in x-rays. How does it spread? The ab­nor­mal cells be­gin break­ing away from the orig­i­nal tu­mour. They can then en­ter blood ves­sels or lymph ves­sels, which branch into tis­sues through­out the en­tire body. This process of can­cer cells trav­el­ling to other body parts and da­m­ag­ing ad­di­tional tis­sues and or­gans is known as metas­ta­sis, and it’s one of the rea­sons that early can­cer de­tec­tion is crit­i­cal to a per­son’s sur­vival rate. What are the risk fac­tors? Most women who get breast can­cer can­not de­ter­mine ex­actly why it hap­pened to them, how­ever there are some known risk fac­tors as­so­ci­ated with this disease. Ob­vi­ously, gen­der is a huge fac­tor, as breast can­cer oc­curs nearly 100 times more in women than in men. How­ever, this doesn’t mean it’s im­pos­si­ble for men to be di­ag­nosed with breast can­cer. So, men should still take no­tice of any un­usual lumps in their breast tis­sue. Most can­cer is di­ag­nosed after the age of 55, and if you have a fam­ily his­tory of breast or ovar­ian can­cer you have an in­creased risk of be­ing di­ag­nosed. Other risk fac­tors in­clude dense breast tis­sue, mak­ing lumps harder to de­tect, as well as cer­tain genome changes, which can be de­ter­mined through ge­netic test­ing. Breast Can­cer by the Num­bers 1 in 8 Cana­dian women will be af­fected by breast can­cer An es­ti­mated 26,300 women and 230 men in Canada will be di­ag­nosed in 2017 There is a 1 in 30 prob­a­bil­ity that a Cana­dian woman will die from breast can­cer in her life­time Breast can­cer mor­tal­ity rates have de­creased by 44% since 1987 In Canada, al­most 5000 women and 43 men will die from breast can­cer in 2017 Breast can­cer makes up 26% of the can­cer di­ag­nosed in Canada Al­though it’s still the most com­mon can­cer di­ag­no­sis in Cana­dian women and the sec­ond lead­ing cause of can­cer deaths in Cana­dian women, fewer women are dy­ing from breast can­cer to­day than in the past. Thanks to ear­lier de­tec­tion made pos­si­ble by ad­vances in screen­ing tech­nol­ogy, raised aware­ness about the im­por­tance of early de­tec­tion, reg­u­lar mam­mo­grams, and im­proved treat­ment meth­ods, the mor­tal­ity rates have de­clined from 41.7 deaths per 100,000 in 1987 to 23.4 deaths per 100,000 in 2016. The Cana­dian Can­cer So­ci­ety rec­om­mends women with an av­er­age risk of de­vel­op­ing breast can­cer to be screened start­ing at the age of 50, with new tests per­formed ev­ery two years. Women aged 40 and above who have a fam­ily his­tory of can­cer should talk to their doc­tor about early screen­ing. Some re­searchers are ex­plor­ing the can­cer and cannabis con­nec­tion, try­ing to de­ter­mine if the ac­tive com­pounds in cannabis may help. These stud­ies in­clude: JunD is in­volved in the an­tipro­lif­er­a­tive ef­fect of Delta9-tetrahy­dro­cannabi­nol on hu­man breast can­cer cells. The en­doge­nous cannabi­noid anan­damide in­hibits nhibits hu­man breast can­cer cell pro­lif­er­a­tion. Delta9-tetrahy­dro­cannabi­nol in­hibits cell cy­cle pro­gres­sion in hu­man breast can­cer cells through Cdc2 reg­u­la­tion. Cannabid­i­olic acid-me­di­ated se­lec­tive down-reg­u­la­tion of c-fos in highly ag­gres­sive breast can­cer MDA-MB-231 cells: pos­si­ble in­volve­ment of its down-reg­u­la­tion in the ab­ro­ga­tion of ag­gres­sive­ness. Cannabi­noids and gliomas. Like with many other med­i­cal con­di­tions, much more re­search needs to hap­pen in or­der to help cure and com­pletely elim­i­nate breast can­cer. In the mean­time, aware­ness and sup­port are im­por­tant steps you can take per­son­ally and within your com­mu­nity, as well as mak­ing sure you and your loved ones are screened as rec­om­mended.

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