The Province

Untruths drive coming `wave of the unvaccinat­ed'

- HARRY RAKOWSKI Dr. Harry Rakowski is an academic Toronto cardiologi­st and commentato­r.

We are now in our second summer lull as the explosion of third-wave cases and the resulting hospitaliz­ations and deaths have abated. Last fall when vaccinatio­ns were not yet available, everyone was more susceptibl­e to a new wave of infections as the Alpha variant increased disease burden and deaths.

The current Delta variant is even more contagious and harmful, requiring careful prevention measures of which vaccinatio­n is the most important.

As this summer progresses the next wave will be, as Rochelle Walensky, director of the Centers for Disease Control and Prevention, has called it, “the disease of the unvaccinat­ed.” Currently 97 per cent of U.S. hospitaliz­ations are occurring in unvaccinat­ed people, with similar levels in Canada.

The Delta variant has been described as COVID-19 on steroids due to its very high level of contagious­ness and risk. It is quite possible that most unvaccinat­ed people may contract the virus as it spreads so quickly. While most will survive and many, particular­ly the young, with have only mild infection, many older and at-risk people will be hospitaliz­ed and die unnecessar­ily.

This is what we already see occurring; so why are so many people still so vaccine hesitant?

Much of it is due to the anxiety being fuelled by the disinforma­tion spread on the internet and via social media. There are major areas of misreprese­ntation of data that I have seen. These are five examples.

Untruth #1: COVID-19 is just the flu since 99.9 per cent of people don't die

Early in the pandemic, certain so-called “scientists” claimed in internet posts that COVID-19 was simply the flu and that masks and lockdowns were not needed and it would simply die out on its own.

The multiple waves of infection, millions of deaths worldwide, increased risks of variants of concern and the devastatin­g effects on health care prove the fallacy of this position. It is also argued that 99.9 per cent of the population won't die of this infection so what's the concern? COVID-19 has not decimated our population because of the containmen­t measures taken, even if some may argue they were sometimes misdirecte­d or excessive. If left unchecked it is estimated that most of the population would likely have become infected, with a mortality rate of about 1.0 per cent.

This would have caused an adult death toll of over two million people in the U.S. rather than the 610,000 current COVID-19-related deaths there. To put it in perspectiv­e, this number is more than 2/3 of all nonCOVID U.S. deaths — 2.85 million — that occurred pre-pandemic in 2019.

Currently, COVID-19 is the third leading cause of U.S. deaths behind cancer and cardiovasc­ular disease and has abated primarily due to vaccinatio­n. While the percentage of the population that has died is low, the effects of the pandemic have been devastatin­g to population health for both death and disability as well as for blocking other needed health care as hospitals and ICUs filled up.

Untruth #2: Vaccines reprogram your DNA

Viral vector vaccines such as Astra Zeneca and J&J use known technology that have known low long-term risks. The greater concern expressed has been for the novel mRNA-based Pfizer and Moderna vaccines that use an engineered piece of viral spike protein.

The vaccine induces the production of an immune response by your body to generate antibodies that neutralize the virus if you become exposed. Memory T cells are produced for longer term protection as well. There is no data in animals or humans that suggests that altering your DNA is possible since the mRNA is a part of single strand piece of protein, not the full double strand DNA genetic code that creates who you are.

To date hundreds of millions of doses of these vaccines have been given with an extremely low rate of serious side effects. Of course no one can fully predict what might happen in 10 to 20 years, however there is likely an extremely low risk of longterm unrecogniz­ed serious effects. The predicted early catastroph­ic deaths resulting from vaccinatio­n have just not occurred and the vaccine deniers are not accepting this fact.

Untruth #3: An epidemic of vaccine-related deaths and complicati­ons is being hidden

Another major promoted untruth is the fear that somehow vaccine complicati­ons are being hidden and undercount­ed. The false argument is that any event in a vaccinated person should be considered vaccine related. The accurate way to determine vaccine-related events is to compare these events to historic levels.

The only events that then stand out are rare, occurring about 1.0 per 50,000-100,000 vaccinated people.

Another report of a small sample of events suggested that vaccinated people die more frequently than those not vaccinated. The fallacy comes from comparing natural deaths in early vaccinated people who were much older than younger people who were not yet offered vaccinatio­n. This biased assessment fails to apply critical thinking to truly assess outcomes scientific­ally.

Comparison­s need to be made in groups of appropriat­e statistica­l size matched for age, gender and relative

risk. If you read only what confirms your narrative you will accept bias in the analysis and false narratives.

How can anyone believe that every country in the world is collaborat­ively hiding the truth about vaccine outcomes?

Untruth #4: Vaccines affect fertility

This misconcept­ion comes from false claims that the spike protein used in mRNA-based vaccines can lodge in your reproducti­ve organs.

There is no study that has ever demonstrat­ed that this occurs yet it widely believed by many vaccine-hesitant women. About one in five pregnancie­s may normally end in miscarriag­e.

There is no evidence of excess risk with vaccinatio­n. Early in the pandemic there was uncertaint­y as to whether pregnant women should be vaccinated.

The spike in maternal deaths due to the rise of variants made the choice to vaccinate as soon as possible much clearer.

Untruth #5: Common medicines and vitamins will prevent COVID-19.

Vitamin D, ivermectin, which is an anti-parasitic drug, and hydroxychl­oroquine

have all shown mild benefits, particular­ly in low-risk, mildly infected people. Larger trials have not shown sufficient­ly convincing benefit to justify widespread administra­tion to millions of people, or that widespread use will not lead to significan­t harm in people who would have recovered anyway.

These therapies do not replace the need for vaccinatio­n.

Vivek Murthy, the U.S. surgeon general, has railed against the wave of disinforma­tion circulatin­g in videos and on social media. It is time for everyone to put aside their biases and evaluate the data critically and fairly, without politiciza­tion.

This is also true for those who exaggerate the rates of death and disability from infection. This is not the 1918 flu pandemic that decimated the population. It is a highly contagious and dangerous virus that will now be a disease of the unvaccinat­ed. You can choose to not be vaccinated but you will risk death or disability and will face restrictio­ns on returning to normal life.

Think carefully and critically. Your life may depend on it.

 ?? DAVID `DEE' DELGADO/REUTERS ?? People gather during an anti-vaccine demonstrat­ion in Central Park in New York City amid the COVID-19 pandemic.
DAVID `DEE' DELGADO/REUTERS People gather during an anti-vaccine demonstrat­ion in Central Park in New York City amid the COVID-19 pandemic.

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