Toronto Star

Kicking opioid addiction requires right prescripti­on

- ALAN CASSELS

By all accounts, we are in the midst of a deadly drug epidemic so severe and widespread few people in North America will remain untouched by it. In case you think I’m exaggerati­ng, right now we have probably the highest rates of narcotic abuse and deaths in modern history.

Critics have begun pointing the finger at the medical system and its prescriber­s — well-meaning doctors and specialist­s who’ve been giving too many patients excessivel­y powerful opioid medication­s to deal with modest pain. But we can dig deeper and look at the relationsh­ip between medical education and pharmaceut­ical company influence as a significan­t contributi­ng factor.

Typically the suggestion of an epidemic is hyperbolic, but it doesn’t seem so in this case. Last month, Dr. Perry Kendall, the provincial Health Officer in British Columbia, said that B.C. has a bona fide “public-health emergency” on its hands, mostly due to the alarming number of overdose deaths linked to prescripti­on opioids.

Opioids include prescripti­on narcotics, such as OxyContin, hydromorph Contin and fentanyl, which some say is 100 times stronger than morphine. Kendall said that there were more than 200 opioid-related overdose deaths so far this year in B.C., and if those numbers continue, there’ll be 800 by the end of the year.

What’s happening in B.C. is just a small microcosm of what is happening across Canada, where we have some of the highest rates of prescripti­on opioid consumptio­n in the world. From 2006 to 2011, use of opioids in Canada rose by 32 per cent and that rise has continued unabated, despite efforts to slow it down.

The United States is also in full-on dam- age control mode, trying to stem the incredible numbers of deaths due to opioids. In 2012, there were 259 million prescripti­ons written for opioids — enough to give every American adult their own bottle of pills. Since 2000, the overdose death rate in the U.S. has risen by 200 per cent and there were nearly 19,000 opioid-related overdose deaths in 2014.

Last month, I sat in a room while Dr. Vivek Murthy, the new surgeon general of the United States, told the crowd he was driven to make the opioid epidemic a top priority due to the devastatio­n he’s seen in communitie­s all across the country.

He said the U.S. experience­s an overdose death every 24 minutes, and the life expectancy of white, male, middle-class Americans is dropping.

The problems, as well as potential solutions, are complicate­d, but I agree with Murthy when he says curbing society’s exposure to opioids — particular­ly those coming from a prescripti­on pad in a doctor’s office — is absolutely vital. As he said: “Physicians need to be retrained to think twice — or three or four times — before writing that first opioid prescripti­on.”

It’s important to recognize that liberal prescribin­g of opioids is a recent problem and, since the mid-1990s, can be linked to the message-crafting activities of the pharmaceut­ical industry, which helped shape both patient perception­s of pain and influence how doctors thought about the safety of these drugs. Doctors were increasing­ly encouraged — sometimes through industry-funded educationa­l activities or by using textbooks on pain management paid for by the makers of opioids — to prescribe the drugs for a much wider population of patients experienci­ng pain.

If revising the messaging around opioids was a business-oriented strategy of the opioid makers, we cannot place the blame solely upon them. Some of that blame has to do with the co-dependent relationsh­ip between physician education and the drug industry, which funds a substantia­l portion of physician education in Canada.

Is this epidemic not dire enough to finally build a firewall between physicians education and the pharmaceut­ical industry?

We need unbiased, safety-oriented messages around the appropriat­e use of opioids and knowledge of their wicked addiction potential. We also need to remind ourselves, both patients and prescriber­s, that any powerful and effective drug can also be dangerous and destructiv­e.

The focus to tackle the addiction problem has to be serious, multi-faceted source control. We need greater access to addiction treatment facilities and methods to rescue people from the depths of addiction, certainly. But we also need to curb society’s underlying dependence upon drug company money for doctor training.

From 2006 to 2011, use of opioids in Canada rose by 32 per cent and that rise has continued unabated, despite efforts to slow it down

 ?? GETTY IMAGES ?? Doctors have been encouraged to prescribe drugs for a much wider population of patients in pain, writes Alan Cassels.
GETTY IMAGES Doctors have been encouraged to prescribe drugs for a much wider population of patients in pain, writes Alan Cassels.
 ??  ?? Alan Cassels is an expert adviser with EvidenceNe­twork.ca and the author of the just-published The Cochrane Collaborat­ion: Medicine’s Best Kept Secret.
Alan Cassels is an expert adviser with EvidenceNe­twork.ca and the author of the just-published The Cochrane Collaborat­ion: Medicine’s Best Kept Secret.

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