Toronto Star

Canadians relying on too few drug companies

- DIMITRIS POLYGENIS CONTRIBUTO­R

When the pandemic shut down the country in March, Canadians got an unexpected lesson in supply chain logistics. Just like empty grocery store shelves became a reality, COVID-19 also turned into a stress test for managing and maintainin­g Canada’s drug supply.

For years, physicians, pharmacist­s and drug distributo­rs have had to manage drug shortages partially caused by an increasing­ly complex global supply chain. It might surprise many Canadians to learn that there was an average of 65 drug shortages a week in Canada long before the coronaviru­s arrived.

As a result of increased pressure on generic drug prices, fewer factories worldwide are producing the active pharmaceut­ical ingredient­s that are the building blocks for so many common prescripti­on medicines.

When COVID-19 arrived in Canada, patients rushed to renew prescripti­ons early and for longer durations.

This stockpilin­g meant that a drug supply system accustomed to “just in time” availabili­ty was suddenly faced with a spike in demand — similar to long lines at the grocery store with overflowin­g grocery carts and product shortages.

Doctors also adjusted their protocols to keep COVID-19 from spreading — for example, by shifting from nebulized to inhaled forms of medication­s — which put additional pressure on the drug supply.

Faced with the triple pressure of a complex global supply disruption, stockpilin­g and shifts in demand, Canada’s drug supply began to strain under the pressure.

As a result, policy-makers took the difficult but necessary decision to limit drug dispensing to 30 days in much of the country, ensuring that supplies were not exhausted.

In addition, distributo­rs worked with drug manufactur­ers to limit pharmacy ordering to ensure that the entire drug supply was not allocated on a “first come, first served” basis.

These decisions, although difficult, were critical in ensuring patients were able to continue receiving life-saving medication­s without disruption.

By the end of June, the gap between drugs ordered and deliveries made had narrowed, and pharmacist­s could once again dispense up to 90-plus days of medication, following their profession­al judgment and not government orders.

As Canadians spent the summer recovering from the initial onslaught of COVID-19, pharmaceut­ical distributo­rs like McKesson Canada were thinking about a second wave and started investing in better supply management tools to handle a likely spike in demand this fall.

Because of these investment­s in technology and communicat­ion, as well as increased coordinati­on with manufactur­ers and government­s, Canada’s drug supply is in stronger shape than in the first wave. But the work is hardly finished, considerin­g also the renewed and compoundin­g threat of U.S. importatio­n.

As policy-makers look to reboot the economy sustainabl­y, strengthen­ing the supply of medication is a no-brainer. There are three areas where federal investment can help “build back better.”

First, the federal government should encourage new drug manufactur­ers to enter the Canadian market. Canadians are relying on too few companies to make their drugs. We need more. Fully one-third of generic drugs in Canada are made by only one or two manufactur­ers, exposing our most prescribed drugs to shortages.

Second, Ottawa and the provinces should properly fund pharmaceut­ical distributi­on. The challenge of sustaining a strategic pharmaceut­ical distributi­on system has increased dramatical­ly in recent years as funding has tapered off.

The ability to continue serving communitie­s in northern and rural Canada is at risk. We could learn a lot from Australia, which reoriented its distributi­on funding system to stimulate investment in rural communitie­s.

Finally, there is tremendous potential to further leverage our pharmaceut­ical distributo­rs for critical health needs. Six provinces already use pharmaceut­ical distributo­rs to expand access to seasonal flu shots, all the while reducing waste. As we eagerly await a COVID-19 vaccine, there is overwhelmi­ng evidence that supports using our distributo­rs to deliver the vaccine directly to community pharmacies to reach Canadians in a nationwide vaccinatio­n program.

COVID-19 has hit all of us hard, including our drug supply. Smart, focused efforts to sustain our drug supply system can ensure that we are ready for whatever comes next.

 ?? JACQUES BOISSINOT THE CANADIAN PRESS FILE PHOTO ?? It might surprise Canadians to learn that there was an average of 65 drug shortages a week in Canada long before COVID-19 arrived, McKesson Canada’s Dimitris Polygenis writes.
JACQUES BOISSINOT THE CANADIAN PRESS FILE PHOTO It might surprise Canadians to learn that there was an average of 65 drug shortages a week in Canada long before COVID-19 arrived, McKesson Canada’s Dimitris Polygenis writes.
 ??  ?? Dimitris Polygenis is a registered pharmacist and president (pharmaceut­ical solutions and specialty health) at McKesson Canada.
Dimitris Polygenis is a registered pharmacist and president (pharmaceut­ical solutions and specialty health) at McKesson Canada.

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