Toronto Star

Drugmaker Pfizer expects to make roughly $15 billion in revenue this year from the COVID-19 vaccine.

Analyst says firm’s success with vaccine represents its new focus on science and innovation

- LINDA A. JOHNSON

Pfizer, the first company to get U.S. emergency use authorizat­ion for a COVID-19 vaccine, swung to a small profit in the fourth quarter as it started shipping vaccines globally.

The drugmaker expects roughly $15 billion (U.S.) in revenue this year from the vaccine, which won emergency clearance in mid-December from U.S. regulators and already has racked up approvals in more than 50 countries. The two-dose vaccine is about 95 per cent effective at preventing coronaviru­s symptoms and is one of only a few vaccines available to check the global pandemic.

Rising medicine sales helped offset big increases in spending on research and production. The New York company is manufactur­ing hundreds of millions of doses of the COVID-19 shot and pushing forward on research gauging its effectiven­ess in different patient groups, such as teens and people with compromise­d immune systems.

Pfizer has said that this year it can produce two billion doses of the vaccine, developed with its German partner BioNTech, including 200 million doses promised for the U.S. by the end of May.

On a conference call with analysts, Pfizer executives said that so far the vaccine appears quite effective against the COVID-19 variants now circulatin­g in multiple countries because it produces such high levels of antibodies. Still, they are researchin­g that issue and believe protecting against COVID-19 could require booster shots every six or 12 months because of variants, much like the flu vaccine.

“We are going to be ready to develop, in less than 100 days, a new vaccine if needed,” to combat new virus strains, CEO Albert Bourla said in an interview.

Evercore ISI analyst Umer Raffat noted that Pfizer’s $15-billion forecast for COVID-19 vaccine revenue this year only covers the doses under contract, which is less than half of the two billion planned.

Pfizer has only disclosed the U.S. price, $1.95 per dose, but said that after the pandemic is under control, a combinatio­n of higher prices and lower costs for manufactur­ing will make it more profitable.

Bourla called Pfizer’s success in developing such a potent vaccine in under a year — something that often takes a decade — the culminatio­n of Pfizer’s decade-long conversion from a diversifie­d drugmaker into one focused on science and innovation.

The company has been remaking itself to focus on high-tech drug developmen­t such as gene therapies it’s now testing for rare diseases. In 2019, it spun off its consumer health product business to help create a joint venture with GlaxoSmith­Kline. Then in November, Pfizer spun off its Upjohn business, which sells older, mostly off-patent drugs such as Viagra, and combined it with Mylan, a top maker of generic pills and the EpiPen auto injector for treating allergic reactions. The new business is called Viatris.

Pfizer said fourth-quarter net income was $594 million, or 10 cents per share. A year earlier, Pfizer posted a loss of $337 million, or six cents per share, mainly due to a big writedown on the value of eczema drug Eucrisa.

Excluding one-time items, adjusted earnings came to 42 cents per share, or four cents shy of Wall Street projection­s.

In afternoon trading, Pfizer shares fell 97 cents, or 2.7 per cent, to $34.83.

The maker of the world’s top-selling vaccine, Prevnar 13 for preventing pneumonia and related bacterial diseases, reported revenue of $11.68 billion, up 12 per cent from 2019’s fourth quarter. That beat Wall Street forecasts for $11.01 billion. Initial COVID-19 vaccine sales late in the year came to $154 million.

For all of 2020, Pfizer reported net income of $9.6 billion, or $1.71 per share, on revenue of $41.9 billion.

 ?? KENA BETANCUR AFP FILE PHOTO VIA GETTY IMAGES ?? Pfizer said after the pandemic is under control, a combinatio­n of higher prices and lower costs for manufactur­ing the vaccine will make it more profitable.
KENA BETANCUR AFP FILE PHOTO VIA GETTY IMAGES Pfizer said after the pandemic is under control, a combinatio­n of higher prices and lower costs for manufactur­ing the vaccine will make it more profitable.

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