Toronto Star

U.S. study finds 1 in 10 get long COVID after variant infection

- LAURAN NEERGAARD

About 10 per cent of people appear to suffer long COVID after an infection of the omicron variant, a lower estimate than earlier in the pandemic, according to a study of nearly 10,000 Americans that aims to help unravel the mysterious condition.

Early findings from the National Institutes of Health’s study highlight a dozen symptoms that most distinguis­h long COVID, the catchall term for the sometimes debilitati­ng health problems that can last for months or years after even a mild case of COVID-19.

Millions worldwide have had long COVID, with dozens of widely varying symptoms including fatigue and brain fog. Scientists still don’t know what causes it, why it only strikes some people, how to treat it — or even how to best diagnose it. Better defining the condition is key for research to get those answers.

“Sometimes I hear people say, ‘Oh, everybody’s a little tired,’ ” said Dr. Leora Horwitz of NYU Langone Health, one of the study authors. “No, there’s something different about people who have long COVID and that’s important to know.”

The new research, published Thursday in the Journal of the American Medical Associatio­n, includes more than 8,600 adults who had COVID-19 at different points in the pandemic, comparing them to another 1,100 who hadn’t been infected.

By some estimates, roughly one in three of COVID-19 patients have experience­d long COVID. That’s similar to NIH study participan­ts who reported getting sick before the omicron variant began spreading in the U.S. in December 2021. That’s also when the study opened, and researcher­s noted that people who already had long COVID symptoms might have been more likely to enrol.

But about 2,230 patients had their first coronaviru­s infection after the study started, allowing them to report symptoms in real time — and only about 10 per cent experience­d long-term symptoms after six months. Prior research has suggested the risk of long COVID has dropped since omicron appeared; its descendant­s still are spreading.

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