Vancouver Sun

HEALTH: GONORRHEA CLOSE TO UNTREATABL­E

‘ Superbug’ strain found in 2008 resistant to all recommende­d antibiotic­s

- BY KATE KELLAND

LONDON — Drug- resistant strains of gonorrhea have spread to countries across the world, the United Nations health agency said on Wednesday, and millions of patients may run out of treatment options unless doctors catch and treat cases earlier.

Scientists reported last year finding a “superbug” strain of gonorrhea in Japan in 2008 that was resistant to all recommende­d antibiotic­s and warned then that it could transform a once easily treatable infection into a global health threat.

The World Health Organizati­on said those fears are now reality with many more

countries, including Australia, France, Norway, Sweden and Britain, reporting cases of the sexually transmitte­d disease resistant to cephalospo­rin antibiotic­s — normally the last option for drugs against gonorrhea.

“Gonorrhea is becoming a major public health challenge,” said Manjula LustiNaras­imhan, from the WHO’s department of reproducti­ve health and research. She said more than 106 million people are newly infected with the disease every year.

“The organism is what we term a superbug — it has developed resistance to virtually every class of antibiotic­s that exists,” she told a briefing in Geneva. “If gonococcal infections become

untreatabl­e, the health implicatio­ns are significan­t.”

Gonorrhea is a bacterial sexually transmitte­d infection which, if left untreated, can lead to pelvic inflammato­ry disease, ectopic pregnancy, stillbirth­s, severe eye infections in babies, and infertilit­y in both men and women.

It is one of the most common sexually transmitte­d diseases in the world and is most prevalent in south and Southeast Asia and sub- Saharan Africa. In the United States alone, says the Centers for Disease Control and Prevention, the number of cases is estimated at about 700,000 a year.

The WHO called for greater vigilance on the correct use of antibiotic­s and more research

into alternativ­e treatments for so- called gonococcal infections.

The emergence of drug- resistant or superbug strains of gonorrhea is caused by unregulate­d access to and overuse of antibiotic­s, which helps fuel natural genetic mutations within the bacteria.

Experts say an added problem with gonorrhea is that its strains tend to retain their genetic resistance to previous antibiotic­s even after their use has been discontinu­ed.

The WHO said it is not yet clear how far or wide drug resistance in gonorrhea has spread, as many countries lack reliable data.

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