Vancouver Sun

The brain as you’ve never seen it

Jaw- dropping illustrati­ons and fascinatin­g facts about our most mysterious organ

- TRACEY TUFNAIL ttufnail@vancouvers­un.com

Beautiful new reference book explores the organ that controls our existence — even though much of the mind is a mystery to even those who study it.

We all have one, even if we accuse some people of only having half, or none at all. But, surprising­ly for an organ that controls all aspects of man’s existence, the human brain is still mostly a mystery, even to the scientists who specialize in studying it.

Professor of anatomy Ken Ashwell has rounded up a slew of brain experts and collated what we do know to create this reference book, which details all aspects of the brain from birth to death.

Ashwell, who works at the University of New South Wales in Sydney, Australia, has done an impressive job of making such a complex subject understand­able.

Starting from a place that most of us occupy ( assuming the reader has no previous knowledge of the subject), he peppers the text with jawdroppin­g images – MRIs, micrograph­s ( photograph­s taken through a microscope), and detailed graphics — which display the brain like you’ve never seen, or thought of it, before.

But think of it we should. Noted neuroscien­tist Richard Restak, called “one of the world’s most important scientific thinkers” by Scientific American and professor of neurology at George Washington Hospital University School of Medicine and Health Sciences in Washington, D. C. has this to say in the book’s foreword:

“In the near future, I believe that neuroscien­ce will be an integral part of everyone’s education. This effort will be justified by the benefits that will accrue from learning about the organ that is responsibl­e for all that we are.”

There’s much to learn, and all of it is fascinatin­g.

The first few chapters cover the basic functions of the brain, nerves and brain chemistry and developmen­t of the brain and spinal cord.

We learn about the parts of the brain and types of cells it contains, and what they do — mysterious sounding things like the reticular formation.

Buried at the core of the brain stem, it plays an important role in a wide variety of functions — movement, the sleep- wake cycle, breathing, heart rate, emotion and blood pressure.

We also learn that part of the cells in the reticular formation are profoundly affected in old age — 30 to 50 per cent are lost from early adulthood to old age, and this is especially noticeable in patients with Alzheimer’s disease ( dementia is covered in more depth in later chapters).

Later chapters explore the senses — taste ( you can taste with your stomach and esophagus as well, I discovered), smell, touch, hearing, vision, balance, accelerati­on and pain. ( An amazing PET scan illustrati­on shows areas of the brain that are active during a cardiac pain attack; scary.)

Gender and sexuality is covered in detail, and both sides of the debate over whether there are gender- or sexuality- related difference­s in brain structure between the sexes are covered. Essentiall­y the difference­s are not great, however one noticeably robust difference is that boys outnumber girls 13 to one on advanced mathematic­al reasoning. By the time we get to chapters covering movement and actions, we have discovered that making a movement requires so much more than the cerebral cortex deciding to make a move and telling the muscle to contract — we need the complex systems that aid muscle activation or our movements would be spasmodic, exhausting and uncontroll­ed.

The final chapters in this book concentrat­e on the thorny questions of consciousn­ess, mood, and psychosis.

Although unable to answer the big questions like “where am I in my brain?” ( unsurprisi­ng since it has confounded countless philosophe­rs for centuries) we can find out things like how we store memories and why memories are much more intense when they are linked with strong emotion — events like 9/ 11 illuminate our memories like the camera’s flash because of the amygdala, a group of nerve cells in the front of the temporal lobe that plays a key role in linking the perception of objects and situations with their emotional significan­ce.

Other sections cover what happens when things go wrong — brain injuries and diseases, concussion­s, spinal cord injuries — and how they affect the autonomic nervous system and can have such devastatin­g consequenc­es.

There is an in- depth section, too, on drugs and their effect on the brain: both legal ones like anesthetic­s, analgesics, antidepres­sants, alcohol, coffee, and cigarettes as well as the legally murky such as cannabis, hallucinog­ens, anabolic steroids and synthetics.

This volume is so much more than a beautifull­y illustrate­d coffee table book, it is both fascinatin­gly detailed and extraordin­arily readable. No reference library, or lover of good books, should be without a copy.

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 ??  ?? This graphic illustrati­on shows how sudden accelerati­on or decelerati­on of the head, combined with head rotation, causes movements of the brain stem that can twist and tear axons ( the process of a nerve cell used to communicat­e). A twisted axon,...
This graphic illustrati­on shows how sudden accelerati­on or decelerati­on of the head, combined with head rotation, causes movements of the brain stem that can twist and tear axons ( the process of a nerve cell used to communicat­e). A twisted axon,...
 ??  ?? An electron micrograph of the apical part of a tastebud ( pink at centre), known as a gustatory caliculus, on the dorsal surface of the tongue. Tastebuds are barrel- shaped organs which extend throughout the thickness of the epithelial layer and...
An electron micrograph of the apical part of a tastebud ( pink at centre), known as a gustatory caliculus, on the dorsal surface of the tongue. Tastebuds are barrel- shaped organs which extend throughout the thickness of the epithelial layer and...
 ??  ?? This coloured scanning electron micrograph ( SEM) shows sensory hair cells from the inner ear. These cells are surrounded by a fluid called endolymph. As sound enters the ear it causes waves to form in the endolymph, which in turn cause the hairs to...
This coloured scanning electron micrograph ( SEM) shows sensory hair cells from the inner ear. These cells are surrounded by a fluid called endolymph. As sound enters the ear it causes waves to form in the endolymph, which in turn cause the hairs to...
 ??  ?? THE BRAIN BOOK: DEVELOPMEN­T, FUNCTION, DISORDER, HEALTH Ken Ashwell, consultant editor ( Firefly Books)
THE BRAIN BOOK: DEVELOPMEN­T, FUNCTION, DISORDER, HEALTH Ken Ashwell, consultant editor ( Firefly Books)

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