Vancouver Sun

Muscle loss means keto diets not a sustainabl­e solution

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I wonder if keto-diet activist Samara Sonmor recorded calorie counts while on “full keto” carbohydra­te deprivatio­n and whether she tested her urine to document excretion of ketones.

As suggested by health sciences professor Jonathan Little, a beneficial effect on insulin levels and weight loss can occur with sensible dietary restrictio­n alone and is less to occur specifical­ly as a result of a ketogenic state.

The brain requires a rich supply of glucose, but following a period of extreme carbohydra­te restrictio­n can adapt to use ketones for energy. During the adaptation period, alternativ­e glucose is synthesize­d from protein amino acids, including that from muscle. Urea is a byproduct of protein-to-glucose conversion, is excreted in urine, and in high concentrat­ion exerts a diuretic effect.

This is not sustainabl­e as the body does not have spare muscle.

Therefore, on “full keto,” initial weight loss can in part result from muscle auto-cannibalis­m and diuresis of tissue water.

Dr. Clifford Chan-Yan, Vancouver

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