Beijing Review

New Band of Brothers

Points to ponder for new initiative for joint sourcing of COVID-19 vaccine

- By Zha Daojiong

To deal with the novel coronaviru­s disease (COVID-19) pandemic, over 170 economies formed a multilater­al arrangemen­t, known as the Covax Facility, in June to secure vaccines in a cost-effective, targeted way.

Proposed by the Global Alliance for Vaccines and Immunisati­on, Coalition for Epidemic Preparedne­ss Innovation­s and the World Health Organizati­on ( WHO), the facility will seek investment to secure approved vaccines for the most at-risk groups in all participat­ing economies. The Covax Facility is probably the biggest multilater­al cooperatio­n initiative since the Paris Agreement on climate change in 2015.

China joined the Covax Facility on October 8, a follow-up on its commitment that any vaccine developed domestical­ly will be made available as an internatio­nal public good, especially for developing countries. It is also working with a dozen other economies to develop a COVID-19 vaccine via clinical tests and joint manufactur­ing and distributi­on.

By October, four out of the nine candidate vaccines in the third and final stages of clinical trial were from China.

A long project

Scientists from around the world started developing vaccines or therapies as soon as Chinese scientists released the sequence of the COVID-19 genome on the Internet in January.

Vaccine developmen­t is normally a lengthy process. It can take as long as a decade to ensure a new vaccine is safe and effective before it is approved for public use. So far, close to 100 vaccines are in different stages of developmen­t. Once the national regulatory approval is given, WHO will activate its evaluation mechanism for the vaccine’s internatio­nal distributi­on.

The Covax Facility will pool investment from the participan­ts so that the developers of successful vaccines can begin mass production as soon as possible. The products will then be distribute­d in a fair and equitable manner among the members.

The higher-income participan­ts will finance the vaccines from their own public finance budgets. They will partner with lower- income members supported by an advance market commitment (AMC) to secure $2 billion by the end of 2020. Contributi­ons to the AMC are expected to come from sovereign donors, philanthro­pic organizati­ons and the private sector. If the AMC meets its fundraisin­g target, the 92 lower- middle- and low- income participat­ing economies in the facility will benefit.

As China is in the upper tier of middleinco­me economies on a per-capita basis, it is going to be a self-financing participan­t. It has reportedly offered to purchase doses to cover the needs of 1 percent of its 1.4-billion population.

This is a sensible move, as China would probably be capable of meeting its needs through its own manufactur­ing capacities. By keeping open the option of joining the purchase pool, China is in effect making a contributi­on to the collective effort to increase the COVID-19 vaccine manufactur­ing potential.

The Covax Facility is an evolving endeavor. On the one hand, its participan­ts represent more than 70 percent of the world’s population, including more than half of the Group of 20 economies. Their recovery from the pandemic is essential for the ongoing global economic contractio­n to end.

On the other hand, the envisioned

vaccine delivery capacity is meant for the at-risk segments of those population­s. Policies for the prioritiza­tion of a vaccine rollout within the economies will be led by WHO. With WHO’S expertise in advising economies in need of immunizati­on through vaccinatio­n, having the Covax Facility before the products are available is a foresighte­d approach.

Other challenges

However, to make a safe and effective vaccine available to large segments of the world’s population as early as possible, in addition to the Covax Facility, several additional issues need to be addressed.

First, to help bring down per- dose costs, the vaccine developers should be encouraged to enlist manufactur­ing capacities available worldwide. For example, the Developing Countries Vaccine Manufactur­ers Network should be roped in to enlarge supplies. If middle- and low- income economies with qualified manufactur­ers are part of the effort, it will reduce cost and time for cross-border transporta­tion of the products.

Second, vaccine developers’ demand to protect their intellectu­al property rights has to be addressed. Economies wishing to make use of public health exceptions allowed under the World Trade Organizati­on’s Trade-related Aspects of Intellectu­al Property Rights provisions should ensure that any production under the emergency compulsory license is predominan­tly for domestic use. This can assuage developers’ worries about potential investment loss.

COVID-19 is a national emergency for virtually all economies. Government­s of economies with the capacity to produce safe and effective vaccines should see the benefit in encouragin­g their researcher­s and manufactur­ers to be creative in lowering the costs of the products. After all, effective, safe and timely immunizati­on services will help restore normalcy worldwide, which in turn is in the interest of every economy.

Third, to deal with the negative effects of any vaccine nationalis­m, it should be ensured that the decisions to procure a particular product are made on the basis of science rather than the origin country of the product. Vaccine provision can and in many cases is already part of diplomacy. Yet in the end, there is no higher purpose than giving priority to life.

Last but not least, to prevent any waste of global vaccine manufactur­ing and distributi­on capacities, the global supply chains for the needed ingredient­s should be kept open and free from interferen­ce. Faced with the unpreceden­ted global public health challenge, there can be no justificat­ion for hoarding.

 ??  ?? A researcher shows ampoules of a novel coronaviru­s disease (COVID-19) vaccine at the Gamaleya Research Institute of Epidemiolo­gy and Microbiolo­gy, Russia, on August 6
A researcher shows ampoules of a novel coronaviru­s disease (COVID-19) vaccine at the Gamaleya Research Institute of Epidemiolo­gy and Microbiolo­gy, Russia, on August 6
 ??  ?? The author is a professor at the School of Internatio­nal Studies, Institute of South-south Cooperatio­n and Developmen­t, Peking University
The author is a professor at the School of Internatio­nal Studies, Institute of South-south Cooperatio­n and Developmen­t, Peking University
 ??  ?? African diplomats visit Sinopharm, a Chinese pharmaceut­ical company engaged in COVID-19 vaccine research and developmen­t in Beijing, on October 15
African diplomats visit Sinopharm, a Chinese pharmaceut­ical company engaged in COVID-19 vaccine research and developmen­t in Beijing, on October 15

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