China Daily (Hong Kong)

INCREASED HOLDINGS

BGI execs up equity stakes as price slumps

- By CHAI HUA in Shenzhen, Guangdong grace@chinadaily­hk.com

Chinese genomics giant BGI, known as the Beijing Genomics Institute previously, announced on Tuesday that seven of its executives have decided to increase their equity holdings in the company, after a two-day stock slump triggered by a series of reports attacking its credibilit­y.

A report from tech news site huxiu revealed some newborns with defects were previously assessed as low risk by BGI’s DNA-based non-invasive prenatal testing. It took the case of a boy with mental disabiliti­es and physical deformitie­s in Hunan province as an example.

The report also criticized some hospitals and doctors in China, saying they rely too much on BGI’s tests, meaning traditiona­l methods, such as amniocente­sis, are neglected.

The report captured attention in both the media and the capital market. As a result, the Shenzhen-based company’s stock fell by the 10 percent daily limit on Monday and Tuesday. That was despite BGI’s statement on Monday that the boy’s defects were not included within the range of its gene testing methods.

The company said it had performed DNA-based noninvasiv­e prenatal testing on 3.1 million pregnant women globally by the end of May, and 2.48 million of their babies were born. It also admitted 70 infants with abnormal chromosome conditions were born due for different reasons and insurance was provided for these families.

DNA-based non-invasive prenatal testing is generally used to test for Down syndrome, and 98 percent of fetuses with the condition can be tested, according to a study in the United Kingdom, said Cheung Ching-lung, assistant professor of the Centre for Genomic Sciences at the Department of Pharmacolo­gy and Pharmacy at the University of Hong Kong.

However, he said, there are also studies showing the percentage is only 90 percent. Therefore, even if the DNA test shows low risk, he advised pregnant women to also conduct an amniocente­sis to confirm the findings. The amniocente­sis test alone could work because it has been in clinical applicatio­n for a long time and the data provided are more adequate, Cheung said.

The DNA-test is not the only doubt about the company’s credibilit­y. Suspicions arose last month when a letter, accusing BGI of bribing officials and defrauding Stateowned assets, was made public. The genetic institutio­n said the letter contains false informatio­n.

In order to “enhance investors’ confidence”, BGI’s executives, including the company’s general manager, chief operations officer and deputy general managers, increased their holdings of the stock. The total value is said to be no less than 30 million yuan ($4.47 million).

After the move, the shares of the Shenzhen-listed enterprise dropped slightly by 0.11 percent on Wednesday, closing at 82.98 yuan.

Yet another factor that pulled down share prices was the expiry of the lock-in period for more than 51 percent of its total share capital — worth roughly about 33.2 billion yuan, according to latest closing prices.

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 ?? YU FANGPING / FOR CHINA DAILY ?? A visitor walks past a board showing big data for genomics in a BGI R&D facility in Qingdao, Shandong province.
YU FANGPING / FOR CHINA DAILY A visitor walks past a board showing big data for genomics in a BGI R&D facility in Qingdao, Shandong province.

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