China Daily (Hong Kong)

Bayer sees rise of more innovative drugs

- By ZHENG YIRAN zhengyiran@chinadaily.com.cn

With China offering a constantly improving business environmen­t, deeper industrial collaborat­ion and more innovation, multinatio­nal corporatio­ns in the pharmaceut­ical industry and Chinese startups will have more growth opportunit­ies, thereby bringing more innovative drugs to the market, said an executive of German life sciences company Bayer.

Juergen Eckhardt, executive vicepresid­ent, said the changes in China’s pharmaceut­ical business environmen­t over the past 30 years have been “dramatic”.

He also heads Leaps by Bayer and the company’s pharmaceut­icals business developmen­t and licensing division.

A venture capitalist since 2002, he has served on more than 25 company boards. He first visited China in 1988. During his latest visit to Beijing in April, he said the developmen­ts in life sciences are “rapid”, and that a number of scientific innovation­s are happening everyday.

Eckhardt said: “China has emerged as a key global innovation source in life sciences, thanks to academic collaborat­ions for advancing scientific research, particular­ly in biotechnol­ogy and medicine.

“We have seen a number of pioneers emerging, who had made great contributi­ons to driving next-generation drug innovation­s.

“The improvemen­t in the country’s business environmen­t is also encouragin­g. Over the years, we have carried out more than 100 research collaborat­ion projects, which led to the discovery and structural analyses of novel targets.”

In November 2023, Bayer announced a partnershi­p with Shanghai Pharma to establish a new site of its incubator Bayer Co Lab Shanghai. The first of its kind in China, it focuses on cutting-edge innovation­s in cell and gene therapy and oncology, aiming to foster early innovation and startups with Bayer’s global innovation network and R&D expertise, and accelerati­ng the conversion of scientific research outcomes into innovative treatments.

In April, the incubator officially kicked off the recruitmen­t of local partners, mainly startups in China.

This year, Bayer and RTW Investment­s announced equity investment­s of $35 million and $127 million, respective­ly, in Jixing Pharmaceut­icals Ltd, a Shanghai-based biopharmac­eutical company. The three parties joined forces to advance the developmen­t of Jixing’s pipeline in the fields of cardiovasc­ular diseases and ophthalmol­ogy.

Wang Hongwei, a professor with the School of Life Sciences and vice-president of Tsinghua University, said China’s biopharmac­eutical industry is still nascent as local companies started in the past decade, and industrial chains in various segments are still forming.

“Because they were born in a relatively new era, they have more advantages in innovation, entreprene­urship, flexibilit­y and efficiency.”

In terms of innovative drug developmen­t, wider and deeper collaborat­ions are increasing­ly seen between Chinese startups and biopharmac­eutical MNCs. The former bring out new possible clinical-stage discoverie­s, while the latter focus more on offering support in finance, techniques, as well as talent in the subsequent stages, Wang said.

“This kind of collaborat­ion has already been formed as an innovative ecosystem in China,” he said.

Currently, Bayer operates two research and developmen­t and innovation centers and six production plants in China. Over the past five years, Bayer has obtained approval for nearly 30 new prescripti­on drugs or new indication­s in China, with new drugs being launched in China almost simultaneo­usly with the other parts of the world, latest data from the company showed.

Zheng Shanjie, head of the National Developmen­t and Reform Commission, said at an earlier forum that China will take solid steps to accelerate the developmen­t of emerging industries.

The NDRC will constantly carry out practical measures, especially in the sectors of life sciences, highend manufactur­ing and digital technologi­es, he said.

Seeing rising business opportunit­ies, a number of pharmaceut­ical MNCs have been laying more emphasis on forging local partnershi­ps in the country. Ever since China optimized COVID-19 control measures last year, more than 20 senior executives from healthcare MNCs, including Bayer, Takeda, Abbot, Medtronic and Merck, have visited the country to forge collaborat­ions.

Zhou Mi, a senior researcher at the Chinese Academy of Internatio­nal Trade and Economic Cooperatio­n in Beijing, said MNCs working with local partners to take advantage of complement­ary capabiliti­es is an inevitable trend.

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Juergen Eckhardt

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