The Heart Doc­tor

Zhou Yu­jie, vice pres­i­dent of Bei­jing Anzhen Hospi­tal

China Pictorial (English) - - Contents - Text by Wen Zhi­hong

Per­cu­ta­neous coro­nary in­ter­ven­tion (PCI), also known as coro­nary an­gio­plasty, is one of the most rev­o­lu­tion­ary tech­ni­cal break­throughs for treat­ing car­dio­vas­cu­lar dis­eases in re­cent medicine his­tory. In 1992, Dutch car­di­ol­o­gist Fer­di­nand Kiemeneij suc­cess­fully per­formed the world’s first tran­sra­dial an­gio­plasty and stent­ing. De­spite the twists and turns dur­ing its global dis­per­sal, this coro­nary treat­ment method re­sulted in fewer com­pli­ca­tions and a lower mor­tal­ity rate, lead­ing to univer­sal ac­cep­tance.

Zhou Yu­jie, a car­dio­vas­cu­lar spe­cial­ist and vice pres­i­dent of Bei­jing Anzhen Hospi­tal, is con­sid­ered a pi­o­neer and cen­tral fig­ure in pro­mot­ing tran­sra­dial an­gio­plasty and in­ter­ven­tion in China. He founded an In­ter­na­tional Tran­sra­dial Car­dio­vas­cu­lar In­ter­ven­tion and Treat­ment Cen­ter at Bei­jing Anzhen Hospi­tal and led his team in car­ry­ing out the first large-scale clin­i­cal prac­tice and train­ing in China in this field. Their ef­forts have given China the high­est pen­e­tra­tion rate of tran­sra­dial in­ter­ven­tion in the world.

Many years ago, Zhou Yu­jie once demon­strated a tran­sra­dial an­gio­plasty along­side Pro­fes­sor Kiemeneij. At that time, they re­ceived push­back and crit­i­cism from some of their watch­ing coun­ter­parts. But this didn’t abate Pro­fes­sor Kiemeneij’s con­fi­dence for the prospects of PCI, nor did it Zhou’s. Although dubbed a “mad­man of tran­sra­dial in­ter­ven­tion,” Zhou main­tains that the only goal of med­i­cal in­no­va­tion is to treat dis­eases at the low­est cost and with min­i­mal pain to pa­tients.

Clear­ing Veins for Life

Through­out his decades-long med­i­cal ca­reer, Zhou has been pri­mar­ily en­gaged in in­ter­ven­tional treat­ment of car­dio­vas­cu­lar dis­eases. PCI is one of the fastest­grow­ing and most ac­tive sub­fields in the realm of car­di­ol­ogy. It in­volves tran­sra­dial catheter­i­za­tion with the help of med­i­cal imag­ing tech­niques. How­ever, not un­til the end of the 20th cen­tury did Chi­nese car­dio­vas­cu­lar pro­fes­sion­als be­gin pay­ing at­ten­tion to tran­sra­dial ac­cess for in­ter­ven­tional treat­ment. Most chose the femoral artery to per­form catheter­i­za­tion. Af­ter re­view­ing many such cases, Zhou re­al­ized that the trans­femoral pro­ce­dure fre­quently re­sulted in se­vere bleed­ing and cor­re­spond­ing com­pli­ca­tions. “Af­ter such a surgery, the pa­tient has to lay flat on a bed for a dozen hours, and the doc­tor must ex­ert con­tin­ued pres­sure on the wound to stop the bleed­ing for four to six hours be­fore re­mov­ing the ar­te­rial sheath,” he ex­plains. “This is an ex­haust­ing process for both pa­tient and doc­tor.”

Due to its lofty rep­u­ta­tion in car­dio­vas­cu­lar dis­ease treat­ment, Bei­jing Anzhen Hospi­tal is per­pet­u­ally crowded with pa­tients from across China. Typ­i­cally, physi­cians in its Car­di­ol­ogy Depart­ment per­form a dozen surg­eries a day. When he was di­rec­tor of the depart­ment’s Ward 12, Zhou of­ten slept on a couch in his of­fice be­cause he needed to re­move ar­te­rial sheathes for pa­tients who fin­ished surg­eries in the day through­out the wee hours. Some­times he and his col­leagues had to treat post­op­er­a­tive com­pli­ca­tions such as edema and hem­or­rhagic shock.

In this con­text, Zhou was ea­ger to find a safer pro­ce­dure that would cause less pain to pa­tients. Around 2000, he no­ticed that some of his Euro­pean and Ja­panese coun­ter­parts be­gan to ap­ply tran­sra­dial in­ter­ven­tion. But Zhou didn’t find a chance to try this tech­nique un­til May 2002 when a pa­tient with angi­itis from Zaozhuang, Shan­dong Prov­ince, asked him to per­form a tran­sra­dial an­gio­plasty from the arm. While on a train to Zaozhuang, Zhou stud­ied a book on the lat­est ad­vances re­ported at a Euro­pean in­ter­ven­tional car­di­ol­ogy con­fer­ence

and imag­ined all pos­si­ble out­comes of the an­gio­plasty over and over.

At the time, lo­cal hos­pi­tals in Zaozhuang lacked spe­cial­ized tran­sra­dial punc­ture in­stru­ments, so Zhou man­aged to place two stents in a blocked blood ves­sel with con­ven­tional catheters. This was the first tran­sra­dial in­ter­ven­tion ever per­formed in a lo­cal hospi­tal, which at­tracted a tele­vi­sion sta­tion to cover the surgery. Less than two hours af­ter the op­er­a­tion, the pa­tient could al­ready use his arm that had been used in treat­ment while tak­ing a shower. Tran­sra­dial in­ter­ven­tion has ob­vi­ous ad­van­tages: Post­op­er­a­tive bleed­ing can be stopped promptly and con­ve­niently, and pa­tients need not rest on a bed for a dozen hours. Clearly, they suf­fer less pain and re­cover more rapidly. More­over, tran­sra­dial in­ter­ven­tion is usu­ally ac­com­pa­nied by fewer com­pli­ca­tions such as bleed­ing, and pa­tients can leave the hospi­tal sooner with a smaller bill. For this rea­son, Zhou be­lieves that this treat­ment method should be­come main­stream for the ma­jor­ity of car­dio­vas­cu­lar pa­tients.

Af­ter­wards, Zhou and his team be­came de­voted to clin­i­cal prac­tice and re­search of tran­sra­dial an­gio­plasty. Zhou di­vided their ef­forts into three stages: The first was about ap­plied re­search in­clud­ing sur­gi­cal tech­niques to avoid var­i­ous com­pli­ca­tions; the sec­ond stage fo­cused on ex­pand­ing the avail­abil­ity of ra­dial ac­cess and ex­plor­ing the pos­si­bil­i­ties of the ul­nar and brachial ar­ter­ies as ac­cess for in­ter­ven­tional treat­ment, as well as so­lu­tions to rel­e­vant prob­lems; the third stage placed pri­or­ity on blood ves­sel pro­tec­tion, dur­ing which time they con­ducted re­search on vas­cu­lar trauma and reap­pli­ca­tion in tran­sra­dial in­ter­ven­tion.

“For a time, many called me a ‘mad­man in in­ter­ven­tional treat­ment’ be­cause I gave up on the femoral artery with a di­am­e­ter of six mil­lime­ters in fa­vor of the ra­dial artery as nar­row as less than two mil­lime­ters,” Zhou ex­plains. More than two decades of clin­i­cal re­search and prac­tice has shown that tran­sra­dial in­ter­ven­tion not only elim­i­nates the need to lie flat for a dozen hours af­ter the op­er­a­tion, but also cuts the mor­tal­ity rate by 28 per­cent and the pos­si­bil­ity of se­vere bleed­ing com­pli­ca­tions by 23 per­cent.

Af­ter years of ap­pli­ca­tion and pop­u­lar­iza­tion, tran­sra­dial in­ter­ven­tion is now used to treat not only mi­nor car­dio­vas­cu­lar ail­ments but also com­pli­cated, dan­ger­ous dis­eases. The es­tab­lish­ment of a tran­sra­dial in­ter­ven­tion sys­tem has not only re­sulted in ra­tio­nal, ef­fec­tive use of med­i­cal re­sources, but also cre­ated tremen­dous eco­nomic and so­cial re­turns. It is es­ti­mated that a sin­gle tran­sra­dial in­ter­ven­tion surgery can save at least 8,000 yuan com­pared to a trans­femoral in­ter­ven­tion surgery. In 2016, more than 1.2 mil­lion tran­sra­dial in­ter­ven­tion oper­a­tions were per­formed in China, which were es­ti­mated to have saved about 10 bil­lion yuan.

As one of the global cham­pi­ons

of min­i­mally in­va­sive PCI, Zhou has not only led his team to delve into re­search of this new in­ter­ven­tional ther­apy, but also de­voted him­self to pro­mot­ing train­ing on the tech­nique both at home and abroad. He pub­lished the book Tran­sra­dial Coro­nary An­giog­ra­phy and In­ter­ven­tion to spread knowl­edge on the treat­ment ap­proach. In ad­di­tion, he has or­ga­nized the In­ter­na­tional Fo­rum on Tran­sra­dial Car­dio­vas­cu­lar In­ter­ven­tion for 11 years straight and has shared cases and ex­pe­ri­ences at nu­mer­ous in­ter­na­tional aca­demic con­fer­ences. Thanks to Zhou and his coun­ter­parts both at home and abroad, in 2012, the Clin­i­cal Prac­tice Guide­lines of the Euro­pean So­ci­ety of Car­di­ol­ogy listed the ra­dial artery as the prime ac­cess for PCI treat­ment. The pop­u­lar­ity rate of tran­sra­dial in­ter­ven­tion has risen from less than 5 per­cent to 90.5 per­cent in China.

Over the years, the preva­lence and mor­tal­ity rates of car­dio­vas­cu­lar dis­eases have been on the rise in China. Ac­cord­ing to the 2018 Re­port on Car­dio­vas­cu­lar Dis­eases in China re­leased by the Na­tional Cen­ter of Car­dio­vas­cu­lar Dis­eases of China, more than 290 mil­lion peo­ple are suf­fer­ing var­i­ous car­dio­vas­cu­lar dis­eases in the coun­try, which con­trib­ute to 40 per­cent of deaths, a fig­ure higher than any other dis­ease. In­ter­ven­tional treat­ment is key to res­cu­ing pa­tients from acute and se­vere car­dio­vas­cu­lar dis­eases.

Zhou and his team fur­ther ex­panded ar­te­rial ac­cess for PCI from the femoral artery to sev­eral ra­dial ar­ter­ies on the up­per arm, pro­vid­ing more “av­enues” for treat­ing hun­dreds of mil­lions of car­dio­vas­cu­lar pa­tients in the world’s largest de­vel­op­ing coun­try. This break­through has global sig­nif­i­cance. Pro­fes­sor Kiemeneij, who was dubbed the “Fa­ther of Tran­sra­dial In­ter­ven­tion” glob­ally, called Zhou the “Chi­nese pi­o­neer in tran­sra­dial in­ter­ven­tion prac­tice,” not­ing that the re­search team at Bei­jing Anzhen Hospi­tal headed by Pro­fes­sor Zhou Yu­jie greatly boosted the de­vel­op­ment of min­i­mally in­va­sive in­ter­ven­tional treat­ment in China and be­came a shin­ing global rep­re­sen­ta­tive for min­i­mally in­va­sive coro­nary in­ter­ven­tion.

State-of-the-art Tech­niques for All

When tran­sra­dial in­ter­ven­tion was first ap­plied in clin­i­cal prac­tice, many of Zhou’s coun­ter­parts from both China and overseas ar­gued that its ex­treme dif­fi­culty would make the ap­proach less prac­ti­cal. In­deed, com­pared to the femoral artery, the ra­dial artery fea­tures a much smaller di­am­e­ter, which makes it hard to be punc­tured and eas­ier to cause prob­lems such as spasm, twisted ar­ter­ies, vari­a­tions and steno­sis dur­ing tran­sra­dial in­ter­ven­tion surg­eries. In this con­text, how is the suc­cess rate of tran­sra­dial in­ter­ven­tion guar­an­teed across the med­i­cal com­mu­nity?

Zhou is con­fi­dent be­cause he be­lieves in his state-of-theart tech­niques. Over decades, he has com­pleted 15,000 pro­ce­dures of coro­nary an­giog­ra­phy and in­ter­ven­tion. His rich clin­i­cal ex­pe­ri­ence has be­stowed on him su­perb med­i­cal skills.

“Medicine is an ap­plied science,” Zhou of­ten tells his stu­dents. “And in most cases, it is an ir­re­versible art with the me­dia of life. In a sur­gi­cal room, a doc­tor needs to con­trol him­self or her­self with ex­pe­ri­ence and tech­niques to solve prob­lems and save lives. We must per­form the surg­eries that oth­ers can­not and give bet­ter per­for­mances than oth­ers can.”

In De­cem­ber 2013, a pa­tient with tachy­car­dia came to Zhou. The pa­tient was fall­ing into tachy­car­dia sev­eral times a week and al­most ev­ery time, he went to the emer­gency room. He had al­ready re­ceived surg­eries at two hos­pi­tals in Bei­jing, but physi­cians had aborted the oper­a­tions half­way due to car­diac per­fo­ra­tion. Af­ter the pa­tient was ad­mit­ted to Bei­jing Anzhen Hospi­tal, Zhou and his col­leagues agreed to ar­range a surgery.

Dur­ing the surgery, Zhou found the sit­u­a­tion more com­pli­cated than he ex­pected: The pa­tient had an ab­nor­mal car­diac struc­ture, and there was a le­sion hid­den deep in a cor­ner of his heart, un­reach­able with con­ven­tional sur­gi­cal ap­proaches. Af­ter two hours of surgery, there was no progress. How­ever, Zhou still didn’t give up.

The pa­tient came from a low-in­come fam­ily in sub­ur­ban Bei­jing. Pre­vi­ous surg­eries and the emer­gency treat­ment costs had al­ready im­posed a heavy fi­nan­cial bur­den on his fam­ily. Zhou was un­wa­ver­ing in his com­mit­ment to help the pa­tient. “For­tu­nately, no com­pli­ca­tions oc­curred dur­ing the surgery,” he re­calls. “I de­cided to try my best to treat the pa­tient.”

A turn­ing point fi­nally ar­rived in the surgery’s third hour. Through per­form­ing a ra­diofre­quency ab­la­tion, Zhou suc­cess­fully re­moved the dys­func­tional tis­sue that was caus­ing the pa­tient’s tachy­car­dia, and he never ex­pe­ri­enced the con­di­tion again.

Zhou of­ten par­tic­i­pates in emer­gency treat­ment when he can. At around 9 p.m. on April 30, 2017, Zhou re­ceived a phone call just be­fore he ar­rived home, in which he was in­formed that a pa­tient with acute my­ocar­dial in­farc­tion was in emer­gency treat­ment and could use his help. As Zhou rushed back to the emer­gency room, the pa­tient’s heart stopped. Doc­tors in the emer­gency depart­ment did all they could, but noth­ing worked. The pa­tient’s rel­a­tives im­plored doc­tors to keep try­ing to save his life.

Upon ar­rival, Zhou and his col­leagues con­tin­ued emer­gency treat­ment for an­other one and half hours, but with­out a pos­i­tive re­sponse from the pa­tient.

By the wee hours of the next day, more than three hours had passed since the on­set of the stroke. At the re­quest of the pa­tient’s fam­ily, Zhou made a risky de­ci­sion: He checked cir­cu­la­tion in the coro­nary artery of the pa­tient who had been de­clared clin­i­cally dead. A tran­sra­dial coro­nary an­giog­ra­phy showed that the three blood-sup­ply­ing ves­sels in the pa­tient’s heart were all blocked. Zhou im­me­di­ately placed two stents in one of the three blood ves­sels that had clearly just been blocked, which re­stored cir­cu­la­tion. Four hours af­ter his heart­beat had stopped, the pa­tient’s heart started beat­ing again. Then, af­ter a se­ries of treat­ments, the pa­tient opened his eyes by 11 a.m. the next day.

Zhou and his col­leagues later sum­ma­rized the fac­tors be­hind the miracle: timely hos­pi­tal­iza­tion, pro­fes­sional car­diac mas­sage, first­class emer­gency treat­ment and post­op­er­a­tive nurs­ing, trust from the pa­tient’s rel­a­tives, bold and ef­fec­tive mea­sures taken by doc­tors, and the spirit of never giv­ing up. The miracle would have not hap­pened if any of these fac­tors had not been present.

The mar­velous emer­gency treat­ment also stunned the world. Be­fore that, no pa­tient with a heart­beat stop­ping for so long had ever been re­vived. An in­ter­na­tional clin­i­cal re­search con­fer­ence awarded Zhou and his team first prize, and the award pre­sen­ta­tion words read: “Life is frag­ile, but mir­a­cles hap­pen when doc­tors do not give up.”

As one of China’s most pres­ti­gious car­di­ol­ogy hos­pi­tals, Bei­jing Anzhen Hospi­tal has re­ceived count­less pa­tients with com­pli­cated heart dis­eases. Due to his out­stand­ing skill, Zhou al­ways plays a cen­tral role in treat­ing these pa­tients. He also con­sis­tently makes break­throughs in clin­i­cal re­search on rarer cases.

In his Con­trast Agents: A Knotty Prob­lem for­coro­nary In­ter­ven­tion, Zhou pro­vides a sys­tem­atic anal­y­sis of the im­pact of con­trast agents used in coro­nary in­ter­ven­tion on the kid­neys. He ever per­formed surg­eries on a pa­tient with an acute my­ocar­dial in­farc­tion who had a trans­planted kid­ney. Dur­ing the surg­eries, Zhou metic­u­lously con­trolled the amount of con­trast agents and used less than half of the nor­mal level to com­plete the imag­ing to avoid in­jur­ing the pa­tient’s trans­planted kid­ney.

Zhou has been ap­plauded for his ef­forts in pro­mot­ing tran­sra­dial in­ter­ven­tion in the in­ter­na­tional car­dio­vas­cu­lar cir­cles. How­ever, he and his team aim higher: They want to ex­plore more world-lead­ing car­diac ther­a­pies. Some of his team fo­cus on the re­search of sys­tem­atic dis­eases such as me­tab­o­lism prob­lems of the heart and the kid­neys plagu­ing many se­niors, and oth­ers com­mit to biomed­i­cal re­search such as nanomedicine and med­i­cal nanorobots. In the com­ing decade, Zhou will be­gin pro­mot­ing the ap­pli­ca­tion of med­i­cal ro­bots in pe­riph­eral car­dio­vas­cu­lar surg­eries and ex­plor­ing do­mes­tic laser ther­a­pies for vas­cu­lar cal­ci­fi­ca­tion to re­move im­pu­ri­ties from the blood and pre­vent car­dio­vas­cu­lar dis­eases at costs com­pa­ra­ble to the price of a cell phone.

Spirit of a Great Doc­tor

When ap­ply­ing for col­leges, Zhou went against his par­ents’ ad­vice and chose Harbin Med­i­cal Univer­sity. Once, he and sev­eral of his class­mates vol­un­teered to trans­port books for their univer­sity’s li­brary, which took sev­eral days of hard work. As a re­ward for his ded­i­ca­tion, the chief li­brar­ian let Zhou choose a book to keep. Zhou thought for a while be­fore se­lect­ing a copy of Ap­plied Car­di­ol­ogy, a text­book com­piled by Chi­nese trail­blaz­ers in car­di­ol­ogy Dong Chenglang and Tao Shouqi. This book kin­dled Zhou’s life-long love af­fair with car­di­ol­ogy. Over the fol­low­ing three decades, Zhou be­came friends with sev­eral pi­o­neer­ing Chi­nese car­di­ol­o­gists, from whom he learned a lot.

When Zhou joined a post­grad­u­ate pro­gram, Pro­fes­sor Tao Shouqi vis­ited Harbin to lec­ture. His tu­tor asked Zhou to ac­com­pany the pres­ti­gious car­di­ol­o­gist. Over the next few days, Zhou es­corted Pro­fes­sor Tao to var­i­ous ac­tiv­i­ties dur­ing the day and slept in the outer room of

the pro­fes­sor’s suite at night.

“I wore a linen shirt, a tie and a pair of leather san­dals,” Zhou re­calls. “On a rainy day, I held an um­brella for Pro­fes­sor Tao when he at­tended an out­door event. Moved by my hos­pi­tal­ity, he pre­dicted I would be­come some­body one day and re­minded me that if I at­tended an in­ter­na­tional con­fer­ence in the fu­ture, I should dress bet­ter, not­ing that the tie didn’t match the wrin­kled short-sleeved linen shirt or a pair of ca­sual san­dals.”

Just as Tao pre­dicted, to­day Zhou is a spe­cial­ist of global fame in the field of PCI. He of­ten speaks at in­ter­na­tional aca­demic con­fer­ences. Even on or­di­nary work­ing days, he usu­ally wears a long-sleeved white shirt and a tie. “This re­minds me I’m a med­i­cal pro­fes­sional and need to con­tinue study­ing and seek­ing in­no­va­tion.”

Dur­ing a post­doc­toral pro­gram at Bei­jing Med­i­cal Univer­sity (now Pek­ing Univer­sity Health Science Cen­ter), Zhou was tu­tored by Pro­fes­sor Wang Li­hui, a Chi­nese pi­o­neer in in­ter­ven­tional car­di­ol­ogy. At the time, Pro­fes­sor Wang’s health was fail­ing due to old age. Even so, she of­ten taught Zhou while wear­ing a cot­ton-padded coat and sit­ting on a sickbed packed with books. She ex­horted Zhou to stay calm and de­vote him­self to med­i­cal re­search.

In the past, when lec­tur­ing else­where, Zhou of­ten brought a heart spec­i­men do­nated by Wu Yingkai, the found­ing pres­i­dent of Bei­jing Anzhen Hospi­tal. Be­fore es­tab­lish­ing Bei­jing Anzhen Hospi­tal, Wu served as pres­i­dent of Fuwai Hospi­tal un­der the Chi­nese Academy of Med­i­cal Sciences.

Wu coined Bei­jing Anzhen Hospi­tal’s motto of “Eq­uity, Dili­gence, Pre­ci­sion and Hon­esty” and pledged to do­nate all of his or­gans to med­i­cal re­search and teach­ing upon his death.

Through words and deeds, those se­nior med­i­cal ex­perts in­spired Zhou to pre­serve and spread the spirit of a great doc­tor through their ded­i­ca­tion, self­less­ness and com­mit­ment to help­ing ev­ery pa­tient with the most advanced med­i­cal tech­niques. Zhou can­not count the towns he has vis­ited to do surg­eries. His foot­prints can be found in al­most ev­ery Chi­nese hospi­tal that has in­tro­duced PCI.

In 2012, with Zhou’s sup­port, sev­eral doc­tors from Bei­jing Anzhen Hospi­tal par­tic­i­pated in a med­i­cal aid mis­sion in the Repub­lic of Guinea in Africa, where they shared their ex­pe­ri­ence in PCI with lo­cal doc­tors. In 2016, Bright Eric King, a PH.D. in car­dio­va­sol­ogy from Ghana, be­came his stu­dent. Zhou hopes that his for­eign stu­dents from de­vel­op­ing coun­tries can bring advanced med­i­cal tech­niques to their homes to help more peo­ple.

In the eyes of his stu­dents, Zhou is a “su­per­man” and a strict teacher. In ad­di­tion to su­perb med­i­cal skills, Zhou is also noted for his pho­to­graphic mem­ory, stu­dious spirit and flu­ent English. The last thing he can be ex­pected to do is to waste time. “Time is more pre­cious than gold,” he says. “With more time, I could save more lives or learn more to bet­ter help pa­tients.”

Al­most ev­ery day Zhou car­ries a bag loaded with var­i­ous elec­tronic de­vices that con­nect him to the in­ter­net. Be­fore smart­phones were ev­ery­where, he equipped each of his stu­dents with a mo­bile hotspot, so that they could “ac­cess the world” via the in­ter­net any­time. Ev­ery time he en­coun­tered dif­fi­cult cases, Zhou would search the in­ter­net for the lat­est tech­niques in treat­ing sim­i­lar cases. He in­structs his stu­dents and younger physi­cians to do the same. “Be­fore check­ing your pa­tients, you need to be fa­mil­iar with all rel­e­vant in­for­ma­tion from sim­i­lar cases from around the world,” he ex­plains.

Zhou taught his stu­dents three ma­jor lessons: to dream of be­ing a great doc­tor, to main­tain a spirit of dili­gence and ded­i­ca­tion, and to gain the abil­ity to re­sist var­i­ous dis­trac­tions. These are what fu­eled his decades-long ca­reer.

Car­dio­vas­cu­lar spe­cial­ist Zhou Yu­jie (third right, front) is con­sid­ered a pi­o­neer and cen­tral fig­ure in pro­mot­ing tran­sra­dial an­gio­plasty and in­ter­ven­tion in China. Zhou and his team fur­ther ex­panded ar­te­rial ac­cess for PCI from the femoral artery to sev­eral ra­dial ar­ter­ies on the up­per arm, pro­vid­ing more “av­enues” for treat­ing hun­dreds of mil­lions of car­dio­vas­cu­lar pa­tients in the world’s largest de­vel­op­ing coun­try. by Dong Fang

Zhou Yu­jie (right) and Pro­fes­sor Fer­di­nand Kiemeneij at­tend the 2010 In­ter­na­tional Fo­rum on Tran­sra­dial Car­dio­vas­cu­lar In­ter­ven­tion, at which Pro­fes­sor Kiemeneij pre­sented med­i­cal records on the world’s first 100 tran­sra­dial in­ter­ven­tion surg­eries to Zhou.

Zhou Yu­jie (left) demon­strates a tran­sra­dial in­ter­ven­tion surgery along­side Dutch car­di­ol­o­gist Fer­di­nand Kiemeneij (right), who suc­cess­fully per­formed the world’s first tran­sra­dial an­gio­plasty, at Bei­jing Anzhen Hospi­tal.

When Zhou Yu­jie (first left) sees pa­tients, his PH.D. stu­dent Bright Eric King (sec­ond left) from Ghana of­ten watches. Zhou hopes that his for­eign stu­dents from de­vel­op­ing coun­tries can bring advanced med­i­cal tech­niques to their homes to help more peo­ple.

Zhou Yu­jie of­ten en­cour­ages stu­dents and doc­tors to par­tic­i­pate in med­i­cal aid mis­sions abroad. This pic­ture shows his post­doc­toral stu­dent Liu Xiaoli (cen­ter) pro­vid­ing epi­demic sur­vey train­ing to lo­cal med­i­cal work­ers dur­ing a med­i­cal aid mis­sion to fight Ebola in the Repub­lic of Guinea in Africa.

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