Process Optimization of Morindae Officinalis Radix Miniature Decoction Pieces

WEI Xiaofeng1, REN Xiaohang2, LI Xiangwei2, LIU Bonan2, SHI Ji1,2,3, JIA Tianzhu1,2,3

1. School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China; 2. Key Laboratory of Analysis of Processing Principle, State Administration of Tradition Chinese Medicine, Dalian 116600, China; 3. Liaoning Research Center of Traditional Chinese Medicine Processing Engineering, Dalian 116600, China

Abstract: Objective To optimize cutting process for Morindae Officinalis Radix miniature decoction pieces; To investigate whether the cutting technology was suitable for Morindae Officinalis Radix from different producing areas. Methods Steaming time, length of decoction pieces, thickness of decoction pieces, and drying temperature were set as influencing factors, and the contents of crystal lanolin, deacetyl levulinic acid, methyl isophorin-1-methyl ether, methyl isophorin, nes sugar, and the rate of ointment and angle of repose were set as evaluation indexes. The orthogonal test was used to optimize the cutting process of Morindae Officinalis Radix miniature decoction pieces, and HPLC fingerprints of Morindae Officinalis Radix miniature decoction pieces from different producing areas were established. Results The optimal cutting process for Morindae Officinalis Radix miniature decoction pieces was steaming 30 min, then cutting into 3 mm length and 1–2 mm width, and the drying temperature was 40 ℃.

Conclusion The optimal cutting process for Morindae Officinalis Radix miniature decoction pieces is easy to conduct, with good applicability.

Keywords: Morindae Officinalis Radix; miniature decoction pieces; cutting process; orthogonal test; HPLC