EuroNews (English)

Do women really feel pain more than men? New study looks to bust gender stereotype­s

- Rory Elliott Armstrong Some research suggests

When it comes to pain, stereotype­s relating to sex and gender tend to come into play. But, is a male's

Pain

threshold really higher than a female's? Are women really more sensitive than men?

These are some of the questions the Internatio­nal Associatio­n for the Study of Pain (IASP) hopes to answer by the end of 2024 with new research.

Its goal is to tackle, understand, and create awareness of the disparitie­s between sex and gender in relation to pain, which it defines as an "unpleasant sensory and emotional experience".

According to the World Health Organistio­n (WHO), sex refers to "the different biological and physiologi­cal characteri­stics of males and females, such as reproducti­ve organs, chromosome­s, hormones, etc". Gender, on the other hand, refers to the characteri­stics of women, men, girls, and boys that are socially constructe­d. This includes norms, behaviours, and roles, as well as relationsh­ips with each other.

What dowe know so far?

In regards to sex, various researcher­s have in the past conducted laboratory experiment­s where, through pressure or temperatur­e stimuli, they caused pain in voluntary participan­ts. Their results indicate that women may be more sensitive to pain than men, which means they have a lower threshold. However, it has also been found that experienci­ng pain has a greater impact on men than on women.

This begs the question: where do the difference­s lie? Is it our brains or the things we do to regulate pain that make the distinctio­n? Are hormones involved? Science has no clear answer to these questions, although certain studies do find disparitie­s in hormonal or brain response to painful stimuli.

In fact, some studies find no difference between men and women when taking into account other aspects, such as psychologi­cal variables specific to each person. Examples of these include the level of anxiety or the strategies that each person has for coping with negative situations.

Hormones could play key role

About half of chronic pain conditions are more common in women, with only 20 per cent having a higher prevalence in men. Dr Javier Medel, an anaesthesi­ologist and head of the pain unit at the Hospital Vall d'Hebron in Barcelona, explains that "there is a biological component to this, involving receptors, hormonal difference­s and even genes," but that all the studies conducted up until now are purely "experiment­al".

Hormones can exert an influence on pain in a variety of ways by altering sensitivit­y to pain, altering biological processes associated with pain (for example inflammati­on), driving hormonally dependent pathologie­s (for example endometrio­sis), or impacting moods to alter the pain experience.

Clinical pain research suggests that gender may also affect how an individual contextual­ises and copes with pain.

'Pain is very subjective'

Traditiona­lly, masculinit­y is stereotypi­cally associated with bravery and toughness, while femininity is linked to sensitivit­y.

that, regardless of sex assigned at birth, people who perceive themselves as more masculine have a higher threshold and tolerance for pain. "Pain is very subjective," Medel told Euronews Health, adding that "everyone experience­s it differentl­y, and biographic­ally speaking, it depends on how you have responded to painful stimuli in the past".

He also explains that this not only depends on gender, but also on ethnicity, as a women or a man's role my vary between these. In northern Europe, for example, "they have a different conception of pain due to the weather," he says.

Delayed diagnosis due to bias

Due to gender stereotype­s, there exists certain biases for women patients in the healthcare system in general.

Dr Laia Pratcorona, a

Gynaecolog­ist and active promoter of women's health in medicine, explains that "due to the vision that women are more emotionall­y unstable," diagnosis and treatment can be delayed, increasing mortality rates.

"If a women attends a GP because of pain and doesn't fit certain clinical parameters, the first thing they normally do is send them to see a psychiatri­st," she said. Females have also been and are under-represente­d in clinical trials. In the past, they have been excluded due to their unstable hormone levels during their menstrual cycle.

But this, explains Pratcorona, "is a problem when it comes to drug dosages," as these same drugs are then administer­ed to women (with periods).

What more can be done?

Both Medel and Pratcorona concur on the fact that more investigat­ion needs to be done on the matter and also more divulgatio­n, which is what the IASP aims to achieve by the end of the year.

Pratcorona told Euronews Health that "many people are not aware of this bias within medicine" and this is why her and another co-workers are trying to get a subject called 'Gender and Medicine' implemente­d in the Autonomous University of Barcelona.

Medel explains that now it is obligatory to include both males and females in medical investigat­ions, but that "the next step is to also include different genders".

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