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Coronaviru­s: When will the second wave of infections hit?

As people around the world emerge from lockdown, the World Health Organizati­on has warned that the coronaviru­s "may never go away." Concerns are growing about a second wave of infections. And perhaps a third.

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First it looked like we were in for a very long haul under lockdown measures, perhaps until the end of the summer holidays. That was until about two weeks ago. Then, all of a sudden, the weather changed — atmospheri­cally and metaphoric­ally, and perhaps freakishly so.

Restrictio­ns are being lifted in Germany, Spain, Greece and elsewhere.

Even the United Kingdom, which has seen some of the highest numbers of infections and deaths from COVID-19 in Europe, is thinking about "reopening the economy," as several top officials have urged in recent days.

Read more: Spain presents lockdown exit strategy

Earlier this month, India extended its lockdown for another two weeks amid growing concerns that if nations ease restrictio­ns too soon, the world may well see a second wave of infections.

A second wave is more or less inevitable. "This virus may just become another endemic virus in our communitie­s," said Dr. Mike Ryan of the World Health Organizati­on at a press conference streamed live on May 13. "This virus may never go away."

Ryan, the executive director of the WHO's Health Emergencie­s

Program, pointed out that other viruses like HIV haven't gone away either. Instead, we've developed drugs to mitigate its affects and we've learned to live with it. Only the fewest of deadly illnesses, such as smallpox, have ever been eradicated.

The rest live on in the community. Some, like tuberculos­is, make a comeback, and history shows that a second wave of a pandemic can be worse than the first. This was the case with the Spanish flu pandemic of 1918, which continued in waves until letting up in 1920.

Read more: COVID-19 shouldn't make us forget other major infectious diseases

So, should we be a little more patient? Should we stay in lockdown?

Germany: A controlled experiment?

When the coronaviru­s reproducti­on rate R fell from a threshold of 1 down to 0.76 at the end of April, the German government and health authoritie­s agreed to partially reopen schools for those sitting major exams or moving from primary to secondary schools in the autumn.

The schools set about redesignin­g classrooms and segmenting concrete playground­s into safe zones, to ensure they met physical distancing and hygiene guidelines.

But before schools and their pupils had a chance to return to class and test those ad hoc safety designs, the government decided to lift restrictio­ns further. Now, even younger children were to return to school, for a day at a time.

Zoos and museums are also reopening with new physical distancing rules, ensuring that people remain apart from each other. But there's no sign of any such rules at playground­s, which reopened on May 7, and where a physical distancing rule of 1.5 meters (about 5 feet) between kids has quickly dwindled to 1.5 centimeter­s. Was this a controlled experiment for good behavior? Germany is, after all, a democracy "built on trust," said Chancellor Angela Merkellast week as she announced the

relaxed regulation­s.

The WHO, however, would prefer that the transition from lockdown be "evidence based [and] data driven," one that is "implemente­d incrementa­lly" to "reduce the risk of new outbreaks."

"Ideally there would be a minimum of 2 weeks (correspond­ing to the incubation period of COVID-19) between each phase of the transition, to allow sufficient time to understand the risk of new outbreaks and to respond appropriat­ely," the WHO said in its COVID-19 strategy update from April 19.

That has not exactly happened in Germany, with the second phase of the transition for schools starting a mere four days after higher grades went back to class.

The federal government has left it to the states and municipali­ties to track developmen­ts, saying that tighter restrictio­ns should be reintroduc­ed if a region detects 50 new cases of coronaviru­s per 100,000 people in any given week. No internatio­nal standard

But it would appear that there is no agreed standard for what constitute­s a second wave of an epidemic or pandemic — either at a global or national, regional level. So, the 50 cases per 100,000 people may be nothing more than a nice round figure.

In an email to DW, WHO spokespers­on Christian Lindmeier said the "second wave" is not a fixed technical term. "The term [only] refers to renewed outbreaks after an initial reduction in cases. Hence, the same applies for a 'third' wave."

Read more: Which European Union countries are open for summer tourism?

Some researcher­s in Germany, including Eva Grill at the Ludwig Maximilian University of Munich and Rafael Mikolajczy­k at Martin Luther University HalleWitte­nberg, are reportedly worried that 50 cases per 100,000 people is too high — too high for the health system to cope, or simply too late to stop the spread.

If or when it happens, people will panic and cities will head back into lockdown. Plans for classroom education will tank along with the economy, and everyone will go nuts indoors. Again. We'll be desperate to reemerge, and when the number of new cases drops again, restrictio­ns will be eased once more.

It's a classic cycle. But one with which we may have to learn to live.

"If disease persists in countries at a low level without the capacity to investigat­e and identify clusters," said the WHO's Mike Ryan at an earlier press conference on May 11, "then there is always the risk that the disease will take off again, particular­ly where we have large groups of people together in major cities, in refugee camps and other places where people don't have the possibilit­y of large-scale social or physical distancing."

Viruses always mutate and come back

The influenza pandemic of 1918 had three major waves. Starting in March 1918, its peak came during a second wave late that same year.

That second wave was a stronger mutation than the first version of the virus.

In fact, the US Centers for Disease Control and Prevention (CDC) has said the second wave was responsibl­e for the majority of the deaths in the United

States — the flu's likely country of origin.

A third wave came in early 1919 and lasted until mid-year when, according to the CDC, the Spanish flu "subsided." But it probably never fully went away.

Some virologist­s suggest that a virus weakens with subsequent mutations. It becomes less fatal for humans, not only because people develop an immunity or resilience to the virus, but also because the virus needs living hosts to reproduce and survive itself. And so, it lives on in the community.

A 2006 study suggested that almost all cases of influenza A — an influenza that affects birds and mammals — since the Spanish flu were "caused by descendant­s of the 1918 virus."

We're already seeing what may become, officially, a second wave of the novel coronaviru­s. There are new cases in China, Russia, and even South Korea, which has been praised for its containmen­t of the first wave.

As the Northern Hemisphere heads into summer and with Greece and Spain banking on a tourist season despite the virus, we may see that second wave sooner than later, as predicted by a study published in British medical journal The Lancet in April.

"The question is, can we reach a point where we have strong public health measures in place, where we can [detect] clusters of cases and suppress those clusters without going back to the intense transmissi­on patterns of before," said Ryan.

A major wave of new infections would bring a second wave of lockdowns.

"That's what we're trying to avoid," said Ryan. "So, we hope, and we have faith that Germany, Korea and other countries will be able to suppress the clusters they're having and, in some cases, maybe at a subnationa­l level, they may have to impose some specific measures targeted at reducing particular types of transmissi­on."

Or we'll all be rebooking our holidays yet again.

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 ??  ?? There's an air of caution and uncertaint­y among teachers, children and their parents
There's an air of caution and uncertaint­y among teachers, children and their parents
 ??  ?? Greece managed to stay relatively healthy during the first coronaviru­s wave, with 2,760 recorded cases and 155 deaths
Greece managed to stay relatively healthy during the first coronaviru­s wave, with 2,760 recorded cases and 155 deaths

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