Deutsche Welle (English edition)

Guillain-Barre syndrome: A sudden paralysis of the arms and legs

In perfect shape one day, flulike symptoms the next ― followed by paralysis. In rare cases, the Johnson & Johnson COVIDvacci­ne can trigger GuillainBa­rre syndrome. What is GBS and how does it affect us?

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The US Food and Drug Administra­tion (FDA) warned on July 12, 2021, that the Janssen (Johnson & Johnson) COVID-19 vaccine can trigger GuillainBa­rre syndrome (GBS) in very rare cases. There have been 100 preliminar­y reports of GBS associated with the vaccine. Ninetyfive of them were severe and required hospitaliz­ation. One person has died from GBS. So far, a total of 12.5 million doses of the vaccine have already been administer­ed in the United States. Therefore, the GBS cases are considered very rare. The Centers for Disease Control and Prevention (CDC) continue to

recommend the Johnson & Johnson vaccine.

People vaccinated with Johnson & Johnson should seek immediate medical attention if they experience any of the following symptoms: tingling sensations, especially in the legs or arms, that worsen or spread to other parts of the body; difficulty walking; difficulty with facial movements, in

cluding speaking, chewing or swallowing; double vision or an inability to move the eyes; or loss of control over bladder or bowel function.

This is not the first time that vaccinatio­ns have been linked to GBS. In Peru, clinical trials of a COVID vaccine manufactur­ed by Chinese company Sinopharm had been halted on December 12, 2020, after a patient developed GBS symptoms. And in the 1970s, there were 450 GBS cases after swine flu vaccinatio­ns.

Because GBS occurs so rarely, a clear causal link between the nerve disease and vaccinatio­n cannot usually be drawn. GBS occurs much more commonly after bacterial or viral infections. It can also be triggered by infection with SARS-CoV-2. This has presented vaccine developers with difficult dilemmas. One example: An AstraZenec­a vaccine trial last year, where a similar autoimmune disease, transverse myelitis, had occurred in one case.

In 2018, DW reported on a GBS patient who became ill after receiving a hepatitis vaccine. In light of recent events, here is the report:

It began with a vaccine

Carsten Kolberg is an athletic man. As a pool attendant and life guard he was until recently easily able to swim 100 meters

in just over a minute. He is also a SCUBA diver, diving in ice-cold water to depths that are beyond the imaginatio­n of most other people.

In his profession, Kolberg needs to be immunized against infectious diseases. As a first responder at an open-air pool, he can easily come into contact with blood or feces.

"The company doctor found out that I needed to refresh my hepatitis B vaccinatio­n," Kolberg recalled. "I had this done before, and never had a problem with it."

 ??  ?? A degenerati­on of the axons - the long extensions of nerve cells - is the main cause of Guillain-Barré syndrome.
A degenerati­on of the axons - the long extensions of nerve cells - is the main cause of Guillain-Barré syndrome.
 ??  ?? Johnson & Johnson's vaccine has been linked to some cases of GBS in the US
Johnson & Johnson's vaccine has been linked to some cases of GBS in the US

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