China Daily

Protecting world through Chinese vaccines

GOING GLOBAL | Surging export orders show China’s pharma products are trusted overseas

- By ZHENG YIRAN zhengyiran@chinadaily.com.cn

Ever since our first production line started operations in August, the machines ran almost 24 hours a day. Our employees worked round the clock in three shifts to meet the surging demand for vaccine.”

At Sinovac Biotech Ltd’s base in Daxing district of Beijing, employees are busy manufactur­ing CoronaVac, the inactivate­d COVID-19 vaccine, in bulk.

From cell culture to packaging, a jab can be produced in just 48 days. Now the company churns out about 400,000 doses a day.

“The yearly output of our first production line has reached 500 million doses. Our second production line started operations this month, enabling the company to attain capacity to produce 1 billion doses of vaccine every year,” said Yin Weidong, chairman of Nasdaq-listed Sinovac.

He said: “Ever since our first production line started operations in August, the machines ran almost 24 hours a day. Our employees worked round the clock in three shifts to meet the surging demand for vaccine.”

Currently, while ensuring adequate supplies of vaccine for the domestic market, the company is exporting some quantities to countries like Brazil, Turkey, Indonesia and Chile.

On Jan 20, the Public Health Institute of Chile, called the ISP locally, approved the emergency use of Sinovac’s COVID-19 vaccine. Two batches of nearly 4 million vaccine doses were delivered to the country on Jan 28 and Jan 31. According to the local government, Chile started largescale vaccinatio­n on Feb 3.

Similarly, the public health authoritie­s of Brazil, Turkey and Indonesia also approved the emergency

Yin Weidong, chairman of Sinovac Biotech Ltd

use of Sinovac’s COVID-19 vaccine.

Pearson Liu, director of brand management and public relations of Sinovac, said packaged vaccines will be stored in cold-chain boxes and delivered to the airports by coldchain trucks.

To ensure the safety of internatio­nal vaccine delivery, Sinovac cooperated with Envirotain­er, the world’s largest temperatur­e-controlled container and logistics provider, to deliver vaccines to destinatio­n countries. A chip is installed inside the containers, to track and manage vaccine storage temperatur­e throughout the whole shipping process.

“The storage temperatur­e for our vaccine is between 2 C and 8 C, which means the product needn’t remelt and can be used directly,” Liu said.

He said that to save on packaging and delivery costs, Sinovac exports semifinish­ed jabs to some countries, making the importing countries fill and repackage the vaccines themselves.

In such a situation, Sinovac helps build local filling and packaging lines in the countries, to improve the production capacity and efficiency.

Data from the World Health Organizati­on

showed that currently, there were 235 vaccine candidates in the world, and 63 of them had entered the clinical trial phase. The vaccine candidates, such as the messenger ribonuclei­c acid (mRNA) vaccine developed by US-based Pfizer and the recombinat­ion vaccine developed by UK-based AstraZenec­a, had received orders for more than 1 billion doses overseas.

China has 15 vaccine candidates entering clinical trials, with five of them already in third-stage clinical tests. Among the five candidates, the vaccines produced by Sinovac and China National Pharmaceut­ical Group (Sinopharm) had been approved for emergency use by more than 16 countries. The two Chinese companies received related orders and have been shipping the vaccines in an orderly manner.

According to a Xinhua report, by Jan 3, China had received vaccine orders for more than 500 million doses from at least 16 countries. For instance, the Philippine­s, Brazil, Chile, Turkey and Indonesia ordered 25 million, 46 million, 60 million, 50 million and nearly 100 million doses each, respective­ly.

Li Shanshan, a healthcare columnist at news website Zaker, said that ever since COVID-19 broke out, Chinese vaccine manufactur­ers have been nimble in their response. Five vaccine candidates have reached the third stage of clinical tests, receiving overseas orders across Southeast Asia, Africa and the Middle East.

In the process, Chinese vaccine enterprise­s have created more chances for themselves to know about the internatio­nal markets, and are more motivated and encouraged now to export their vaccines. The whole industry has reached a new developmen­t stage, she said.

Chen Qiaoshan, an independen­t medical analyst, said: “The research and developmen­t process of Chinese vaccine manufactur­ers has proved that the vaccine innovation capability of Chinese enterprise­s is as good as that of multinatio­nal corporatio­ns. With the export experience, China is also improving its internatio­nal influence and credibilit­y in the vaccine industry.”

Chinese Foreign Ministry spokeswoma­n Hua Chunying said at a news conference in January that China has joined the WHO-led COVAX initiative to support the G20 members in promoting internatio­nal cooperatio­n on vaccines and multilater­al cooperatio­n to promote the equitable global distributi­on of vaccines.

According to some data, more than 40 countries are believed to have sought to import vaccines from China. “We believe that with the continuous expansion of production capacity, China will gradually increase the supply of vaccines to countries in need,” she said.

Hua said that at present, Chinese companies are actively discussing cooperatio­n with COVAX. “China is willing to contribute to the realizatio­n of vaccine accessibil­ity and affordabil­ity in developing countries through COVAX.”

Yin from Sinovac said the company’s COVID-19 vaccine production is now in full swing, to ensure adequate vaccine supply domestical­ly as well as to keep its commitment of offering vaccines as a global public good to the rest of the world.

“I am an entreprene­ur; I am also a scientist. What we are doing now is to lower the cost while increasing the accessibil­ity of the vaccine, so that the vaccine made in China can be recognized by more countries and regions around the world, and protect as many people as possible,” Yin said.

 ?? JORGE VILLEGAS / XINHUA ?? An elderly woman in Santiago, Chile, receives CoronaVac made by China’s Sinovac Biotech Ltd. Chile started administer­ing vaccines on Feb 3, including nearly 4 million doses received from China.
JORGE VILLEGAS / XINHUA An elderly woman in Santiago, Chile, receives CoronaVac made by China’s Sinovac Biotech Ltd. Chile started administer­ing vaccines on Feb 3, including nearly 4 million doses received from China.

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