VIT works on aptamer-based POC diagnostic kit for COVID-19

A research team from the Vellore Institute of Technology (VIT) has recently bagged a project, funded by the Science and Engineering Research Board (SERB) of the Department of Science & Technology (DST), to develop an aptamer-based point-of-care (POC) diagnostic kit for the detection of COVID-19. An aptamer-based biosensor, also called aptasensor (APTAS), comprises of biorecognition element that detects the target of interest, which then undergoes transduction, to produce a detectable signal. Aptasensor uses aptamers as a biorecognition element, which favours more benefits over antibodies. When aptamer conjugated nanoparticles and lateral flow assay technology are integrated, it shows colour with spike protein of coronavirus, a breakthrough that could enable rapid, instant, accurate and real-time testing among a huge population. It would be highly sensitive and more user friendly.