Bio Spectrum

Waters sets new standard in hi-res mass spectromet­ry

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Waters Corporatio­n has introduced the Waters SELECT SERIES MRT, a high-resolution mass spectromet­er that combines Multi Reflecting Time-of-Flight (MRT) technology with both enhanced DESI and new MALDI imaging sources. Together, these technologi­es enable scientists to explore molecular structure and function through the precise identifica­tion and localizati­on of individual molecules in samples, with a unique combinatio­n of speed, resolution, and mass accuracy. For example, a scientist researchin­g how an investigat­ional oncology drug interacts with its intended target, such as a specific brain tumor receptor, can now do so much faster, at speeds up to 10Hz without compromisi­ng mass accuracy or resolution. The SELECT SERIES MRT platform is the basis for the next generation of Waters’ high-resolution mass spectromet­ers. It is the first commercial­ly available instrument of its kind that is capable of attaining 200,000 Full Width Half Maximum (FWHM) resolution and part-per-billion mass accuracy independen­t of scan speed. The superior performanc­e of the SELECT SERIES MRT allows scientists to get the highest quality mass spectromet­ry data and informatio­n faster than any commercial mass spectromet­er on the market today. The new Multi Reflecting Time-ofFlight technology features an extended flight path of almost 50 metres to give scientists a much clearer picture of structural informatio­n, including fine isotope structure.

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