Bio Spectrum

Mynvax offers ‘warm vaccine’ for COVID-19

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Biotech startup Mynvax, incubated at the Indian Institute of Science (IISc) in Bengaluru, has developed heat-tolerant COVID-19 vaccine formulatio­ns. Published in the peer-reviewed ACS Infectious Diseases journal, researcher­s showed the vaccine formulatio­ns triggered a strong immune response in mice, protected hamsters from the virus, and remained stable at 37 degrees up to a month and at 100 degrees for up to 90 minutes. Most vaccines require refrigerat­ion to remain effective, like Oxford-AstraZenec­a which must be kept between 2 and 8 degrees and Pfizer which requires specialise­d cold storage at -70 degrees. The data shows that all formulatio­ns of Mynvax tested result in antibodies capable of consistent and effective neutralisa­tion of the Alpha, Beta, Gamma and Delta SARS-CoV-2 variants of concern.

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