Bio Spectrum

TechInvent­ion offers single dose COVID-19 vaccine

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TechInvent­ion Lifecare, a biotech startup company based out of Mumbai, has claimed positive outcomes of its recombinan­t subunit SARS-CoV-2 vaccine (CoviTech) in a single dose preliminar­y study. The company is now advancing further developmen­t of the vaccine. In CoviTech, the antigen is expressed in yeast Pichia pastoris, one of the most desirable expression platforms in recombinan­t technology to produce cost-effective products with high yield and easy scale-up process. Products like the Hepatitis B vaccine manufactur­ed using the same platform technology are being administer­ed even to newborns with exceptiona­l safety, according to the company sources. While CoviTech is being positioned as an affordable, effective and safe vaccine for the masses, the startup is also exploring another vaccine candidate targeting the conserved and immunogeni­c regions of the virus. This vaccine may have the potential to address the burning issue of mutations.

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