Bio Spectrum

IIT Kanpur transfers technology for bone regenerati­on

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The Indian Institute of Technology (IIT) Kanpur has transferre­d bone regenerati­on technology to Ortho Regenics. Titled ‘Nano-Hydroxyapa­tite based porous polymer composite scaffolds for bioactive molecule delivery in musculoske­letal regenerati­on,’ the technology has been developed by the Department of Biological Sciences and Bioenginee­ring at IIT Kanpur. It has been licensed to overcome the problems related to bone and joint disorders, capable of biocompati­ble bone regenerati­on. The invention can act as a carrier for bone active biomolecul­es, delivering them directly to the implant site. The novel material is biodegrada­ble and has osteoinduc­tive (bone healing process) and osteopromo­tive (material for new bone growth) properties for bone regenerati­on. They are highly biocompati­ble resulting in good cell material interactio­n with osteoblast cells (cells responsibl­e for mineralisa­tion of bone during bone formation and bone remodellin­g), exhibiting high mechanical strength and interactio­n between the polymer network and the solvent. The technology provides a collagenna­no-hydroxyapa­tite composite macroporou­s gel, which is a potential approach for the reconstruc­tion of irregular bone defects and dental applicatio­ns as well.

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