Agi­lent in­tro­duces NGS based so­lu­tion for ge­netic dis­or­ders

BioSpectrum (Asia) - - SUPPLIER NEWS -

Agi­lent Tech­nolo­gies Inc. re­cently an­nounced the in­tro­duc­tion of

Agi­lent OnePGT, a genome-wide, next-gen­er­a­tion se­quenc­ing (NGS) so­lu­tion for preim­plan­ta­tion ge­netic test­ing (PGT). OnePGT al­lows par­al­lel de­tec­tion of mul­ti­ple mono­genic dis­or­ders (PGT-M), translo­ca­tions (PGT-SR), and ane­u­ploi­dies (PGT-A) on a sin­gle biopsy. OnePGT guides the lab­o­ra­tory from biopsy ma­te­rial to a sin­gle com­pre­hen­sive re­port in a mat­ter of days. Em­pow­ered by Agi­lent’s Alissa plat­form, data anal­y­sis is stream­lined by the op­ti­mized and ver­i­fied pipe­lines, al­low­ing au­to­matic call­ing of ge­netic ab­nor­mal­i­ties with built-in qual­ity con­trol met­rics and au­dit trail. This in­no­va­tive so­lu­tion pro­vides fer­til­ity spe­cial­ists the abil­ity to more eas­ily achieve com­pre­hen­sive PGT data in which to support en­hanced em­bryo rank­ing, iden­ti­fy­ing the best qual­ity em­bryos for trans­fer. As the ma­ter­nal age at con­cep­tion in­creases, the chance of chro­mo­so­mal ab­nor­mal­i­ties within the em­bryo also in­crease lead­ing to lower im­plan­ta­tion rates and in­creased rate of mis­car­riages.

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