BioSpectrum Asia

Korea unveils handheld cancer diagnostic sans radiation exposure

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A team of scientists at the Pohang University of Science and Technology (POSTECH) in South Korea has developed a handheld photoacous­tic finder that can help examine lymph node conditions without radiation exposure. Cancers such as breast cancer and melanoma metastasis­e primarily through the lymphatic system, so knowing the condition of the lymph nodes is essential in accessing the stage and prognosis of cancer. The handheld photoacous­tic finder

(PAF) is equipped with a solidstate dye laser and a transparen­t ultrasound transducer (TUT).

Unlike convention­al gamma probes, this non-radioactiv­e PAF eliminates the risk of exposure to radiation and the need for special facilities and allows repeated usage which is cost-effective. In general, a sentinel lymph node (SLN) biopsy around the cancer is performed to assess the metastasis in breast cancers and melanoma. This is because the SLN is the first gateway for tumours to travel to the lymph nodes. However, since convention­al biopsies use radioisoto­pes to find the SLN, patients and physicians are inevitably exposed to radiation and the procedure requires a special facility to access radioactiv­e materials. The photoacous­tic finder (PAF) system is the first portable photoacous­tic sensing tool for SNL localisati­on.

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